Atrial fibrillation ablation: Reaching the mainstream

John D. Fisher, Michael A. Spinelli, Disha Mookherjee, Andrew K. Krumerman, Eugen C. Palma

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Introduction and Aims: Ablation of atrial fibrillation (AF) has evolved rapidly in the decade since its inception. We aimed to review the results of this evolution as reflected in the published literature. Methods: Publications through 2005 were reviewed, and data included if there was information on the technique used, and follow-up of at least 6 months. Results: More than 23,000 patients met criteria for inclusion. There has been a steady improvement in reported outcomes (P < 0.001). Variations on radiofrequency catheter ablation for pulmonary vein isolation result in apparent elimination ("cure") or improvement of AF in 75%, and surgical techniques are even better. Conclusions: Catheter ablation of AF is now a mainstream procedure. Continuing technical advances are needed to achieve better results with more uniformity and reduced procedure times.

Original languageEnglish (US)
Pages (from-to)523-537
Number of pages15
JournalPACE - Pacing and Clinical Electrophysiology
Issue number5
StatePublished - May 1 2006


  • Ablation
  • Atrial fibrillation
  • Mapping
  • Radiofrequency
  • Review

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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