Atrial Fibrillation Ablation and Stroke

Philip Aagaard; David Briceno; Zoltan Csanadi; Sanghamitra Mohanty; Carola Gianni; Chintan Trivedi; Edina Nagy-Baló; Stephan Danik; Conor Barrett; Francesco Santoro; J. David Burkhardt; Javier Sanchez; Andrea Natale; Luigi Di Biase

doi:10.1016/j.ccl.2015.12.012

Atrial Fibrillation Ablation and Stroke

Philip Aagaard, David Briceno, Zoltan Csanadi, Sanghamitra Mohanty, Carola Gianni, Chintan Trivedi, Edina Nagy-Baló, Stephan Danik, Conor Barrett, Francesco Santoro, J. David Burkhardt, Javier Sanchez, Andrea Natale, Luigi Di Biase

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Catheter ablation has become a widely available and accepted treatment to restore sinus rhythm in atrial fibrillation patients who fail antiarrhythmic drug therapy. Although generally safe, the procedure carries a non-negligible risk of complications, including periprocedural cerebral insults. Uninterrupted anticoagulation, maintenance of an adequate ACT during the procedure, and measures to avoid and detect thrombus build-up on sheaths and atheters during the procedure, appears useful to reduce the risk of embolic events. This is a review of the incidence, mechanisms, impact, and methods to reduce catheter ablation related cerebral insults.

Original language	English (US)
Pages (from-to)	307-316
Number of pages	10
Journal	Cardiology clinics
Volume	34
Issue number	2
DOIs	https://doi.org/10.1016/j.ccl.2015.12.012
State	Published - May 2016
Externally published	Yes

Keywords

Anticoagulation
Atrial fibrillation
Silent cerebral ischemia
Stroke

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.ccl.2015.12.012

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title = "Atrial Fibrillation Ablation and Stroke",

abstract = "Catheter ablation has become a widely available and accepted treatment to restore sinus rhythm in atrial fibrillation patients who fail antiarrhythmic drug therapy. Although generally safe, the procedure carries a non-negligible risk of complications, including periprocedural cerebral insults. Uninterrupted anticoagulation, maintenance of an adequate ACT during the procedure, and measures to avoid and detect thrombus build-up on sheaths and atheters during the procedure, appears useful to reduce the risk of embolic events. This is a review of the incidence, mechanisms, impact, and methods to reduce catheter ablation related cerebral insults.",

keywords = "Anticoagulation, Atrial fibrillation, Silent cerebral ischemia, Stroke",

author = "Philip Aagaard and David Briceno and Zoltan Csanadi and Sanghamitra Mohanty and Carola Gianni and Chintan Trivedi and Edina Nagy-Bal{\'o} and Stephan Danik and Conor Barrett and Francesco Santoro and Burkhardt, {J. David} and Javier Sanchez and Andrea Natale and {Di Biase}, Luigi",

note = "Funding Information: Disclosures: Dr P. Aagaard reports that he has no conflicts of interest. Dr L. Di Biase is a consultant for Biosense Webster, Stereotaxis, and St Jude Medical and has received speaker honoraria/travel from Pfizer, Janssen, EpiEP, Biotronik, and Boston Scintific. Dr A. Natale is a consultant for Biosense Webster and St Jude Medical and has received speaker honoraria/travel from Medtronic, Boston Scientific, Biotronik, and Janssen. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = may,

doi = "10.1016/j.ccl.2015.12.012",

language = "English (US)",

volume = "34",

pages = "307--316",

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T1 - Atrial Fibrillation Ablation and Stroke

AU - Aagaard, Philip

AU - Briceno, David

AU - Csanadi, Zoltan

AU - Mohanty, Sanghamitra

AU - Gianni, Carola

AU - Trivedi, Chintan

AU - Nagy-Baló, Edina

AU - Danik, Stephan

AU - Barrett, Conor

AU - Santoro, Francesco

AU - Burkhardt, J. David

AU - Sanchez, Javier

AU - Natale, Andrea

AU - Di Biase, Luigi

N1 - Funding Information: Disclosures: Dr P. Aagaard reports that he has no conflicts of interest. Dr L. Di Biase is a consultant for Biosense Webster, Stereotaxis, and St Jude Medical and has received speaker honoraria/travel from Pfizer, Janssen, EpiEP, Biotronik, and Boston Scintific. Dr A. Natale is a consultant for Biosense Webster and St Jude Medical and has received speaker honoraria/travel from Medtronic, Boston Scientific, Biotronik, and Janssen. Publisher Copyright: © 2016 Elsevier Inc.

PY - 2016/5

Y1 - 2016/5

N2 - Catheter ablation has become a widely available and accepted treatment to restore sinus rhythm in atrial fibrillation patients who fail antiarrhythmic drug therapy. Although generally safe, the procedure carries a non-negligible risk of complications, including periprocedural cerebral insults. Uninterrupted anticoagulation, maintenance of an adequate ACT during the procedure, and measures to avoid and detect thrombus build-up on sheaths and atheters during the procedure, appears useful to reduce the risk of embolic events. This is a review of the incidence, mechanisms, impact, and methods to reduce catheter ablation related cerebral insults.

AB - Catheter ablation has become a widely available and accepted treatment to restore sinus rhythm in atrial fibrillation patients who fail antiarrhythmic drug therapy. Although generally safe, the procedure carries a non-negligible risk of complications, including periprocedural cerebral insults. Uninterrupted anticoagulation, maintenance of an adequate ACT during the procedure, and measures to avoid and detect thrombus build-up on sheaths and atheters during the procedure, appears useful to reduce the risk of embolic events. This is a review of the incidence, mechanisms, impact, and methods to reduce catheter ablation related cerebral insults.

KW - Anticoagulation

KW - Atrial fibrillation

KW - Silent cerebral ischemia

KW - Stroke

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Atrial Fibrillation Ablation and Stroke

Abstract

Keywords

ASJC Scopus subject areas

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