Atraumatic quantitation of cerebral perfusion in cats by 19f magnetic resonance imaging

Craig A. Branch, James R. Ewing, J. A. Helpern, R. J. Ordidge, Shazad Butt, K. M.A. Welch

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (paCO2 = 39 ± 4 mm Hg) and hypercapnia (paCO2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

Original languageEnglish (US)
Pages (from-to)39-53
Number of pages15
JournalMagnetic Resonance in Medicine
Volume28
Issue number1
DOIs
StatePublished - Nov 1992
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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