Atraumatic quantitation of cerebral perfusion in cats by 19f magnetic resonance imaging

Craig A. Branch; James R. Ewing; J. A. Helpern; R. J. Ordidge; Shazad Butt; K. M.A. Welch

doi:10.1002/mrm.1910280105

Atraumatic quantitation of cerebral perfusion in cats by ¹⁹f magnetic resonance imaging

Craig A. Branch, James R. Ewing, J. A. Helpern, R. J. Ordidge, Shazad Butt, K. M.A. Welch

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15 Scopus citations

Abstract

We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (p_aCO₂ = 39 ± 4 mm Hg) and hypercapnia (p_aCO₂ = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

Original language	English (US)
Pages (from-to)	39-53
Number of pages	15
Journal	Magnetic Resonance in Medicine
Volume	28
Issue number	1
DOIs	https://doi.org/10.1002/mrm.1910280105
State	Published - Nov 1992
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Atraumatic quantitation of cerebral perfusion in cats by 19f magnetic resonance imaging",

abstract = "We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (paCO2 = 39 ± 4 mm Hg) and hypercapnia (paCO2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.{\textcopyright} 1992 Academic Press,Inc.",

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AU - Branch, Craig A.

AU - Ewing, James R.

AU - Helpern, J. A.

AU - Ordidge, R. J.

AU - Butt, Shazad

AU - Welch, K. M.A.

PY - 1992/11

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N2 - We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (paCO2 = 39 ± 4 mm Hg) and hypercapnia (paCO2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

AB - We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (paCO2 = 39 ± 4 mm Hg) and hypercapnia (paCO2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

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Atraumatic quantitation of cerebral perfusion in cats by ¹⁹f magnetic resonance imaging

Abstract

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