Atorvastatin: Beyond lipid-lowering effects in the diabetic population

Julie Ramos, Qamar A. Khan, Martin Thoenes, Bobby V. Khan

Research output: Contribution to journalArticlepeer-review

Abstract

Statins are the mainstay of therapy in coronary artery disease and hypercholesterolemia. Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor that is taken once daily. It has been shown to considerably reduce cardiovascular mortality events. Recently, several trials have demonstrated that atorvastatin has pleiotropic effects beyond its lipid-lowering capacities. Atorvastatin is especially beneficial in diabetics for stroke prevention and improving cardiovascular mortality risk.

Original languageEnglish (US)
Pages (from-to)527-533
Number of pages7
JournalFuture Cardiology
Volume2
Issue number5
DOIs
StatePublished - Sep 2006
Externally publishedYes

Keywords

  • 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
  • Atorvastatin
  • Cerebrovascular accident
  • Coronary heart disease
  • Diabetes mellitus

ASJC Scopus subject areas

  • Molecular Medicine
  • Cardiology and Cardiovascular Medicine

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