TY - JOUR
T1 - Association of neighborhood segregation with 6-year incidence of metabolic syndrome in the Hispanic community health study/study of Latinos
AU - Pichardo, Catherine M.
AU - Pichardo, Margaret S.
AU - Gallo, Linda C.
AU - Talavera, Gregory A.
AU - Chambers, Earle C.
AU - Sanchez-Johnsen, Lisa A.P.
AU - Pirzada, Amber
AU - Roy, Amanda L.
AU - Rodriguez, Carmen
AU - Castañeda, Sheila F.
AU - Durazo-Arvizu, Ramon A.
AU - Perreira, Krista M.
AU - Garcia, Tanya P.
AU - Allison, Matthew
AU - Carlson, Jordan
AU - Daviglus, Martha L.
AU - Plascak, Jesse J.
N1 - Funding Information:
This research was supported by NCI training grant: T32CA057699 . The Hispanic Community Health Study/Study of Latinos is a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina ( HHSN268201300001I / N01-HC-65,233 ), University of Miami ( HHSN268201300004I / N01-HC-65,234 ), Albert Einstein College of Medicine ( HHSN268201300002I / N01-HC-65,235 ), University of Illinois at Chicago ( HHSN268201300003I / N01- HC-65,236 Northwestern Univ ), and San Diego State University ( HHSN268201300005I / N01-HC-65,237 ). The following Institutes/Centers/Offices have contributed to the HCHS/SOL through a transfer of funds to the NHLBI: National Institute on Minority Health and Health Disparities,
Funding Information:
This research was supported by NCI training grant: T32CA057699. The Hispanic Community Health Study/Study of Latinos is a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (HHSN268201300001I / N01-HC-65,233), University of Miami (HHSN268201300004I / N01-HC-65,234), Albert Einstein College of Medicine (HHSN268201300002I / N01-HC-65,235), University of Illinois at Chicago (HHSN268201300003I / N01- HC-65,236 Northwestern Univ), and San Diego State University (HHSN268201300005I / N01-HC-65,237). The following Institutes/Centers/Offices have contributed to the HCHS/SOL through a transfer of funds to the NHLBI: National Institute on Minority Health and Health Disparities, National Institute on Deafness and Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, NIH Institution-Office of Dietary Supplements. The authors thank the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants, who generously contributed their time and provided the study data. The authors also thank the HCHS/SOL staff members for their dedication and expertise. A complete list of staff and investigators was published in the Annals of Epidemiology 2010; 20:642–649 and is also available on the study website (http://www.cscc.unc.edu/hchs). The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Publisher Copyright:
© 2022
PY - 2023/2
Y1 - 2023/2
N2 - Purpose: Examine the association between neighborhood segregation and 6-year incident metabolic syndrome (MetSyn) in the Hispanic Community Health Study/Study of Latinos. Methods: Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have MetSyn at baseline. The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and Q). Results: Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR = 1.53, 95% CI = 1.082.17; Q5, OR = 2.29, 95% CI = 1.493.52). Economic concentrationprivilege (continuous OR = 0.87, 95% CI = 0.770.98), racial concentrationracialized privilege (Q1 (greater concentration) vs. Q2 OR = 0.75, 95% CI = 0.541.04; Q3 OR = 0.68, 95% CI = 0.441.05; Q4 OR = 0.68, 95% CI = 0.451.01; Q5 OR = 0.64, 95% CI = 0.420.98)(continuous OR = 0.93, 95% CI = 0.821.04), and racialized economic concentrationprivilege (i.e., higher SES non-Hispanic White, continuous OR = 0.86, 95% CI = 0.760.98) were associated with lower disease odds. Conclusion: Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident MetSyn compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.
AB - Purpose: Examine the association between neighborhood segregation and 6-year incident metabolic syndrome (MetSyn) in the Hispanic Community Health Study/Study of Latinos. Methods: Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have MetSyn at baseline. The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and Q). Results: Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR = 1.53, 95% CI = 1.082.17; Q5, OR = 2.29, 95% CI = 1.493.52). Economic concentrationprivilege (continuous OR = 0.87, 95% CI = 0.770.98), racial concentrationracialized privilege (Q1 (greater concentration) vs. Q2 OR = 0.75, 95% CI = 0.541.04; Q3 OR = 0.68, 95% CI = 0.441.05; Q4 OR = 0.68, 95% CI = 0.451.01; Q5 OR = 0.64, 95% CI = 0.420.98)(continuous OR = 0.93, 95% CI = 0.821.04), and racialized economic concentrationprivilege (i.e., higher SES non-Hispanic White, continuous OR = 0.86, 95% CI = 0.760.98) were associated with lower disease odds. Conclusion: Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident MetSyn compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.
KW - Hispanic/Latino
KW - Metabolic syndrome
KW - Neighborhood segregation
KW - Racialized economic concentration
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U2 - 10.1016/j.annepidem.2022.11.003
DO - 10.1016/j.annepidem.2022.11.003
M3 - Article
C2 - 36473628
AN - SCOPUS:85144390903
VL - 78
SP - 1
EP - 8
JO - Annals of Epidemiology
JF - Annals of Epidemiology
SN - 1047-2797
ER -