TY - JOUR
T1 - Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users
AU - Howard, Andrea A.
AU - Klein, Robert S.
AU - Schoenbaum, Ellie E.
N1 - Funding Information:
Financial support: National Institute of Drug Abuse (grants RO1 DA13248 and R01 DA04347).
PY - 2003/5/15
Y1 - 2003/5/15
N2 - We performed a cross-sectional analysis of factors associated with diabetes mellitus among 557 drug users who were recruited from a methadone treatment program and were participating in a longitudinal study of hepatitis C virus (HCV) infection. We found that HCV infection was strongly associated with diabetes mellitus (adjusted odds ratio [OR], 2.9; 95% confidence interval [CI], 1.3-6.4) after controlling for age, race, unemployment, and body mass index. Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1-15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5-20.4]).
AB - We performed a cross-sectional analysis of factors associated with diabetes mellitus among 557 drug users who were recruited from a methadone treatment program and were participating in a longitudinal study of hepatitis C virus (HCV) infection. We found that HCV infection was strongly associated with diabetes mellitus (adjusted odds ratio [OR], 2.9; 95% confidence interval [CI], 1.3-6.4) after controlling for age, race, unemployment, and body mass index. Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1-15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5-20.4]).
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U2 - 10.1086/374838
DO - 10.1086/374838
M3 - Article
C2 - 12746779
AN - SCOPUS:0037846082
SN - 1058-4838
VL - 36
SP - 1318
EP - 1323
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 10
ER -