Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users

Andrea A. Howard, Robert S. Klein, Ellie E. Schoenbaum

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45 Scopus citations


We performed a cross-sectional analysis of factors associated with diabetes mellitus among 557 drug users who were recruited from a methadone treatment program and were participating in a longitudinal study of hepatitis C virus (HCV) infection. We found that HCV infection was strongly associated with diabetes mellitus (adjusted odds ratio [OR], 2.9; 95% confidence interval [CI], 1.3-6.4) after controlling for age, race, unemployment, and body mass index. Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1-15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5-20.4]).

Original languageEnglish (US)
Pages (from-to)1318-1323
Number of pages6
JournalClinical Infectious Diseases
Issue number10
Publication statusPublished - May 15 2003


ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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