Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users

Andrea A. Howard, Robert S. Klein, Ellie Schoenbaum

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We performed a cross-sectional analysis of factors associated with diabetes mellitus among 557 drug users who were recruited from a methadone treatment program and were participating in a longitudinal study of hepatitis C virus (HCV) infection. We found that HCV infection was strongly associated with diabetes mellitus (adjusted odds ratio [OR], 2.9; 95% confidence interval [CI], 1.3-6.4) after controlling for age, race, unemployment, and body mass index. Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1-15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5-20.4]).

Original languageEnglish (US)
Pages (from-to)1318-1323
Number of pages6
JournalClinical Infectious Diseases
Volume36
Issue number10
DOIs
StatePublished - May 15 2003

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Hepatitis C
Drug Users
Diabetes Mellitus
Odds Ratio
Virus Diseases
Confidence Intervals
Infection
Protease Inhibitors
Hepacivirus
Unemployment
Methadone
Therapeutics
Longitudinal Studies
Body Mass Index
Cross-Sectional Studies
HIV

ASJC Scopus subject areas

  • Immunology

Cite this

Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users. / Howard, Andrea A.; Klein, Robert S.; Schoenbaum, Ellie.

In: Clinical Infectious Diseases, Vol. 36, No. 10, 15.05.2003, p. 1318-1323.

Research output: Contribution to journalArticle

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