Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy

Leah S. Gendler, Sheldon M. Feldman, Ronald Balassanian, Mary A. Riker, Stanley K. Frencher, Denise B. Whelan, Shalini Anne, Joshua D. Gross, Jean Marc Cohen, Susan K. Boolbol

Research output: Contribution to journalReview article

61 Citations (Scopus)

Abstract

The management of papillary lesions identified on image-guided breast biopsy remains controversial. In the literature, data regarding papillary lesions are limited because of small sample sizes. The purpose of this study was to identify the prevalence of atypical ductal hyperplasia and malignancy associated with papillary lesions identified on image-guided breast biopsy. This study is a retrospective review of 9,310 consecutive image-guided biopsies performed at our institution between January 1996 and November 2003. Patients were included if they underwent an excisional biopsy after a papillary lesion was diagnosed on image-guided biopsy. Papillary lesions were identified in 153 (2%) of the 9,310 image-guided biopsies performed, and 87 of these patients underwent subsequent excisional biopsy at our institution. Breast cancer (in situ or invasive) was identified in 15 patients (17%), and 16 patients (18%) had atypical ductal hyperplasia identified at excisional biopsy. These data suggest that excisional biopsy should be considered when a papillary lesion is identified at percutaneous image-guided breast biopsy. The final surgical pathology may impact the treatment plan, risk reduction, and/or surveillance for more than a third of patients diagnosed with a papillary lesion on image-guided biopsy.

Original languageEnglish (US)
Pages (from-to)365-370
Number of pages6
JournalAmerican Journal of Surgery
Volume188
Issue number4 SPEC. ISS.
DOIs
StatePublished - Oct 1 2004
Externally publishedYes

Fingerprint

Image-Guided Biopsy
Breast
Breast Neoplasms
Biopsy
Carcinoma, Intraductal, Noninfiltrating
Surgical Pathology
Risk Reduction Behavior
Sample Size

Keywords

  • Atypical ductal hyperplasia
  • Breast cancer
  • Core-needle biopsy
  • Fine-needle aspiration
  • Image-guided biopsy
  • Papillary lesion
  • Papilloma

ASJC Scopus subject areas

  • Surgery

Cite this

Gendler, L. S., Feldman, S. M., Balassanian, R., Riker, M. A., Frencher, S. K., Whelan, D. B., ... Boolbol, S. K. (2004). Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy. American Journal of Surgery, 188(4 SPEC. ISS.), 365-370. https://doi.org/10.1016/j.amjsurg.2004.06.026

Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy. / Gendler, Leah S.; Feldman, Sheldon M.; Balassanian, Ronald; Riker, Mary A.; Frencher, Stanley K.; Whelan, Denise B.; Anne, Shalini; Gross, Joshua D.; Cohen, Jean Marc; Boolbol, Susan K.

In: American Journal of Surgery, Vol. 188, No. 4 SPEC. ISS., 01.10.2004, p. 365-370.

Research output: Contribution to journalReview article

Gendler, LS, Feldman, SM, Balassanian, R, Riker, MA, Frencher, SK, Whelan, DB, Anne, S, Gross, JD, Cohen, JM & Boolbol, SK 2004, 'Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy', American Journal of Surgery, vol. 188, no. 4 SPEC. ISS., pp. 365-370. https://doi.org/10.1016/j.amjsurg.2004.06.026
Gendler, Leah S. ; Feldman, Sheldon M. ; Balassanian, Ronald ; Riker, Mary A. ; Frencher, Stanley K. ; Whelan, Denise B. ; Anne, Shalini ; Gross, Joshua D. ; Cohen, Jean Marc ; Boolbol, Susan K. / Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy. In: American Journal of Surgery. 2004 ; Vol. 188, No. 4 SPEC. ISS. pp. 365-370.
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