Association of Baseline Neuropsychological Function and Progression of Illness Over 4 Years in HIV-Seropositive Individuals

Charles H. Silberstein; Mary Alice O’dowd; Ellie E. Schoenbaum; Gerald H. Friedland; Patricia Chartock; Cheryl Feiner; F. Patrick Mckegney

doi:10.1016/S0033-3182(93)71824-1

Association of Baseline Neuropsychological Function and Progression of Illness Over 4 Years in HIV-Seropositive Individuals

Charles H. Silberstein, Mary Alice O’dowd, Ellie E. Schoenbaum, Gerald H. Friedland, Patricia Chartock, Cheryl Feiner, F. Patrick Mckegney

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV-positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Haistead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.

Original language	English (US)
Pages (from-to)	502-505
Number of pages	4
Journal	Psychosomatics
Volume	34
Issue number	6
DOIs	https://doi.org/10.1016/S0033-3182(93)71824-1
State	Published - 1993

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Applied Psychology
Psychiatry and Mental health

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abstract = "The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV-positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Haistead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.",

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AU - Chartock, Patricia

AU - Feiner, Cheryl

AU - Patrick Mckegney, F.

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Association of Baseline Neuropsychological Function and Progression of Illness Over 4 Years in HIV-Seropositive Individuals

Abstract

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