Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals

C. H. Silberstein, Mary A. O'Dowd, Ellie Schoenbaum, G. H. Friedland, P. Chartock, C. Feiner, F. P. McKegney

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV- positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.

Original languageEnglish (US)
Pages (from-to)502-505
Number of pages4
JournalPsychosomatics
Volume34
Issue number6
StatePublished - 1993

Fingerprint

HIV
Neuropsychological Tests
Virus Diseases
Disease Progression
Central Nervous System
Progression
AIDS/HIV
Illness

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals. / Silberstein, C. H.; O'Dowd, Mary A.; Schoenbaum, Ellie; Friedland, G. H.; Chartock, P.; Feiner, C.; McKegney, F. P.

In: Psychosomatics, Vol. 34, No. 6, 1993, p. 502-505.

Research output: Contribution to journalArticle

Silberstein, CH, O'Dowd, MA, Schoenbaum, E, Friedland, GH, Chartock, P, Feiner, C & McKegney, FP 1993, 'Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals', Psychosomatics, vol. 34, no. 6, pp. 502-505.
Silberstein, C. H. ; O'Dowd, Mary A. ; Schoenbaum, Ellie ; Friedland, G. H. ; Chartock, P. ; Feiner, C. ; McKegney, F. P. / Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals. In: Psychosomatics. 1993 ; Vol. 34, No. 6. pp. 502-505.
@article{c0142254925242fdb599749dbb181919,
title = "Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals",
abstract = "The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV- positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.",
author = "Silberstein, {C. H.} and O'Dowd, {Mary A.} and Ellie Schoenbaum and Friedland, {G. H.} and P. Chartock and C. Feiner and McKegney, {F. P.}",
year = "1993",
language = "English (US)",
volume = "34",
pages = "502--505",
journal = "Psychosomatics",
issn = "0033-3182",
publisher = "American Psychiatric Publishing Inc.",
number = "6",

}

TY - JOUR

T1 - Association of baseline neuropsychological function and progression of illness over 4 years in HIV-seropositive individuals

AU - Silberstein, C. H.

AU - O'Dowd, Mary A.

AU - Schoenbaum, Ellie

AU - Friedland, G. H.

AU - Chartock, P.

AU - Feiner, C.

AU - McKegney, F. P.

PY - 1993

Y1 - 1993

N2 - The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV- positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.

AB - The authors conducted a study to examine the association between neuropsychological markers of central nervous system impairment and systemic human immunodeficiency virus (HIV) disease progression in a sample of 64 HIV- positive asymptomatic patients who were followed for a median of 45.6 months. Patients with poorer baseline scores on the Halstead-Reitan Trail-Making A neuropsychological test developed HIV-related systemic symptoms earlier over the study period than patients with the higher scores on the same test (P < 0.05). Subclinical neuropsychological dysfunction in otherwise asymptomatic HIV-infected individuals may be a harbinger of progressive HIV-related immunologic dysfunction.

UR - http://www.scopus.com/inward/record.url?scp=0027445421&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027445421&partnerID=8YFLogxK

M3 - Article

C2 - 8284340

AN - SCOPUS:0027445421

VL - 34

SP - 502

EP - 505

JO - Psychosomatics

JF - Psychosomatics

SN - 0033-3182

IS - 6

ER -