Association between neuropsychiatric morbidity and streptococcal infections in children

S. Viswanathan; P. D. Moses; S. Varkki; P. S. Russell; K. N. Brahmadathan

doi:10.1007/s13312-010-0026-1

Association between neuropsychiatric morbidity and streptococcal infections in children

S. Viswanathan, P. D. Moses, S. Varkki, P. S. Russell, K. N. Brahmadathan

Research output: Contribution to journal › Article › peer-review

Abstract

We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 - 10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.

Original language	English (US)
Pages (from-to)	168-170
Number of pages	3
Journal	Indian pediatrics
Volume	47
Issue number	2
DOIs	https://doi.org/10.1007/s13312-010-0026-1
State	Published - Feb 2010
Externally published	Yes

Keywords

Neuropsychiatric disorders
PANDAS
Streptococcal infection

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1007/s13312-010-0026-1

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title = "Association between neuropsychiatric morbidity and streptococcal infections in children",

abstract = "We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 - 10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.",

keywords = "Neuropsychiatric disorders, PANDAS, Streptococcal infection",

author = "S. Viswanathan and Moses, {P. D.} and S. Varkki and Russell, {P. S.} and Brahmadathan, {K. N.}",

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AU - Moses, P. D.

AU - Varkki, S.

AU - Russell, P. S.

AU - Brahmadathan, K. N.

PY - 2010/2

Y1 - 2010/2

N2 - We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 - 10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.

AB - We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 - 10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.

KW - Neuropsychiatric disorders

KW - PANDAS

KW - Streptococcal infection

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SP - 168

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JO - Indian pediatrics

JF - Indian pediatrics

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Association between neuropsychiatric morbidity and streptococcal infections in children

Abstract

Keywords

ASJC Scopus subject areas

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