Association between neuropsychiatric morbidity and streptococcal infections in children

S. Viswanathan, P. D. Moses, S. Varkki, P. S. Russell, K. N. Brahmadathan

Research output: Contribution to journalArticle

Abstract

We conducted a case control study to study the association between neuropsychiatric morbidity and group A streptococcal infections in children. Twenty two cases of neuropsychiatric morbidity were compared with 64 controls. Fourteen (63.6%) of the 22 cases were positive for ASO and/or ADNB while 21 of the 64 controls (32.8%) were positive for either or both antibodies (OR = 3.428; CI: 1.15 - 10.18; P=0.026). We conclude that there is a statistically significant association between neuropsychiatric morbidity and streptococcal infection in children.

Original languageEnglish (US)
Pages (from-to)168-170
Number of pages3
JournalIndian Pediatrics
Volume47
Issue number2
DOIs
Publication statusPublished - Feb 1 2010
Externally publishedYes

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Keywords

  • Neuropsychiatric disorders
  • PANDAS
  • Streptococcal infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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