Association between herpes simplex virus-1 infection and idiopathic unilateral facial paralysis in children and adolescents

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11 Citations (Scopus)

Abstract

We studied the association between herpes simplex virus-1 (HSV-1) infection and Bell palsy in children. Thirty-three of 42 affected patients had a positive HSV-1 enzyme-linked immunosorbent assay compared with 16 of 41 controls (P ≤ 0.0003). Ten of 47 affected patients had a positive HSV-1 polymerase chain reaction compared with 4 of 45 of controls (P ≤ 0.08). Our findings support an association between HSV-1 infection and Bell palsy in children.

Original languageEnglish (US)
Pages (from-to)468-469
Number of pages2
JournalPediatric Infectious Disease Journal
Volume27
Issue number5
DOIs
StatePublished - May 2008

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Bell Palsy
Human Herpesvirus 1
Virus Diseases
Enzyme-Linked Immunosorbent Assay
Polymerase Chain Reaction

Keywords

  • Bell palsy
  • facial paralysis
  • HSV-1

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

Cite this

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abstract = "We studied the association between herpes simplex virus-1 (HSV-1) infection and Bell palsy in children. Thirty-three of 42 affected patients had a positive HSV-1 enzyme-linked immunosorbent assay compared with 16 of 41 controls (P ≤ 0.0003). Ten of 47 affected patients had a positive HSV-1 polymerase chain reaction compared with 4 of 45 of controls (P ≤ 0.08). Our findings support an association between HSV-1 infection and Bell palsy in children.",
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AU - Mayers, Marguerite M.

AU - Avner, Jeffrey R.

AU - Fox, Amy S.

AU - Herold, Betsy

AU - Goldman, David L.

PY - 2008/5

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AB - We studied the association between herpes simplex virus-1 (HSV-1) infection and Bell palsy in children. Thirty-three of 42 affected patients had a positive HSV-1 enzyme-linked immunosorbent assay compared with 16 of 41 controls (P ≤ 0.0003). Ten of 47 affected patients had a positive HSV-1 polymerase chain reaction compared with 4 of 45 of controls (P ≤ 0.08). Our findings support an association between HSV-1 infection and Bell palsy in children.

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