TY - JOUR
T1 - Association between BMI and periodontitis in women living with or at risk for HIV
AU - Janorkar, Deepti A.
AU - Long, Dustin M.
AU - Weber, Kathleen M.
AU - Sharma, Anjali
AU - Lin, Guo Hao
AU - D'Souza, Gypsyamber
AU - Edmonds, Andrew
AU - Kassaye, Seble
AU - Lahiri, Cecile D.
AU - Konkle-Parker, Deborah
N1 - Funding Information:
Data in this manuscript were collected by the MACS/WIHS Combined Cohort Study (MWCCS). The contents of this publication are solely the responsibility of the authors and do not represent the official views of the National Institutes of Health (NIH). MWCCS (Principal Investigators): Atlanta CRS (Ighovwerha Ofotokun, Anandi Sheth, and Gina Wingood), U01‐HL146241; Baltimore CRS (Todd Brown and Joseph Margolick), U01‐HL146201; Bronx CRS (Kathryn Anastos and Anjali Sharma), U01‐HL146204; Brooklyn CRS (Deborah Gustafson and Tracey Wilson), U01‐HL146202; Data Analysis and Coordination Center (Gypsyamber D'Souza, Stephen Gange and Elizabeth Golub), U01‐HL146193; Chicago‐Cook County CRS (Mardge Cohen and Audrey French), U01‐HL146245; Chicago‐Northwestern CRS (Steven Wolinsky), U01‐HL146240; Northern California CRS (Bradley Aouizerat, Jennifer Price, and Phyllis Tien), U01‐HL146242; Los Angeles CRS (Roger Detels and Matthew Mimiaga), U01‐HL146333; Metropolitan Washington CRS (Seble Kassaye and Daniel Merenstein), U01‐HL146205; Miami CRS (Maria Alcaide, Margaret Fischl, and Deborah Jones), U01‐HL146203; Pittsburgh CRS (Jeremy Martinson and Charles Rinaldo), U01‐HL146208; UAB‐MS CRS (Mirjam‐Colette Kempf, Jodie Dionne‐Odom, and Deborah Konkle‐Parker), U01‐HL146192; UNC CRS (Adaora Adimora), U01‐HL146194; K23AI124913 to Cecile Lahiri. The MWCCS is funded primarily by the National Heart, Lung, and Blood Institute (NHLBI), with additional co‐funding from the Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD), National Institute On Aging (NIA), National Institute Of Dental & Craniofacial Research (NIDCR), National Institute Of Allergy And Infectious Diseases (NIAID), National Institute Of Neurological Disorders And Stroke (NINDS), National Institute Of Mental Health (NIMH), National Institute On Drug Abuse (NIDA), National Institute Of Nursing Research (NINR), National Cancer Institute (NCI), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Minority Health and Health Disparities (NIMHD), and in coordination and alignment with the research priorities of the National Institutes of Health, Office of AIDS Research (OAR). MWCCS data collection is also supported by UL1‐TR000004 (UCSF CTSA), UL1‐TR003098 (JHU ICTR), UL1‐TR001881 (UCLA CTSI), P30‐AI‐050409 (Atlanta CFAR), P30‐AI‐073961 (Miami CFAR), P30‐AI‐050410 (UNC CFAR), P30‐AI‐027767 (UAB CFAR), and P30‐MH‐116867 (Miami CHARM).
Funding Information:
Data in this manuscript were collected by the MACS/WIHS Combined Cohort Study (MWCCS). The contents of this publication are solely the responsibility of the authors and do not represent the official views of the National Institutes of Health (NIH). MWCCS (Principal Investigators): Atlanta CRS (Ighovwerha Ofotokun, Anandi Sheth, and Gina Wingood), U01-HL146241; Baltimore CRS (Todd Brown and Joseph Margolick), U01-HL146201; Bronx CRS (Kathryn Anastos and Anjali Sharma), U01-HL146204; Brooklyn CRS (Deborah Gustafson and Tracey Wilson), U01-HL146202; Data Analysis and Coordination Center (Gypsyamber D'Souza, Stephen Gange and Elizabeth Golub), U01-HL146193; Chicago-Cook County CRS (Mardge Cohen and Audrey French), U01-HL146245; Chicago-Northwestern CRS (Steven Wolinsky), U01-HL146240; Northern California CRS (Bradley Aouizerat, Jennifer Price, and Phyllis Tien), U01-HL146242; Los Angeles CRS (Roger Detels and Matthew Mimiaga), U01-HL146333; Metropolitan Washington CRS (Seble Kassaye and Daniel Merenstein), U01-HL146205; Miami CRS (Maria Alcaide, Margaret Fischl, and Deborah Jones), U01-HL146203; Pittsburgh CRS (Jeremy Martinson and Charles Rinaldo), U01-HL146208; UAB-MS CRS (Mirjam-Colette Kempf, Jodie Dionne-Odom, and Deborah Konkle-Parker), U01-HL146192; UNC CRS (Adaora Adimora), U01-HL146194; K23AI124913 to Cecile Lahiri. The MWCCS is funded primarily by the National Heart, Lung, and Blood Institute (NHLBI), with additional co-funding from the Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD), National Institute On Aging (NIA), National Institute Of Dental & Craniofacial Research (NIDCR), National Institute Of Allergy And Infectious Diseases (NIAID), National Institute Of Neurological Disorders And Stroke (NINDS), National Institute Of Mental Health (NIMH), National Institute On Drug Abuse (NIDA), National Institute Of Nursing Research (NINR), National Cancer Institute (NCI), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Minority Health and Health Disparities (NIMHD), and in coordination and alignment with the research priorities of the National Institutes of Health, Office of AIDS Research (OAR). MWCCS data collection is also supported by UL1-TR000004 (UCSF CTSA), UL1-TR003098 (JHU ICTR), UL1-TR001881 (UCLA CTSI), P30-AI-050409 (Atlanta CFAR), P30-AI-073961 (Miami CFAR), P30-AI-050410 (UNC CFAR), P30-AI-027767 (UAB CFAR), and P30-MH-116867 (Miami CHARM).
Publisher Copyright:
© 2022 Special Care Dentistry Association and Wiley Periodicals LLC.
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Aims: Currently, there is no data available assessing the association between body mass index (BMI) and periodontitis among women living with HIV (WLWH). This study aims to investigate this association among WLWH and women at risk for HIV (WRH) in the United States. Methods and results: Data from 351 WLWH and 52 WRH participants from the Women's Interagency HIV Study having pocket depths and clinical periodontal attachment loss assessments in 2003–2004 were included. Multinomial logistic regression analyses in the full sample assessed the relationship between BMI (underweight/normal, overweight, or obese) and periodontitis by severity (mild, moderate, severe), adjusting for study sites, age, education, annual household income, smoking, alcohol consumption, and diabetes. Overall, 75.2% women (76.0% WLWH; 69.0% WRH) had periodontitis. Moreover, 75.0% obese and 75.3% overweight women were affected by periodontitis. In the full sample, adjusted odds ratio (aOR) of having mild, moderate, and severe periodontitis in obese women were: 1.14 (95% confidence interval [CI]: 0.51–2.52), 1.02 (95% CI: 0.46–2.29), and 0.24 (95% CI: 0.06–1.07), respectively, and in overweight women: 0.70 (95% CI: 0.31–1.58), 0.85 (95% CI: 0.38–1.90), and 0.31 (95% CI: 0.08–1.15), respectively. Conclusions: Even with high prevalence of periodontitis among women with or without HIV infection in this cohort, this study does not provide evidence of an association between BMI and periodontitis.
AB - Aims: Currently, there is no data available assessing the association between body mass index (BMI) and periodontitis among women living with HIV (WLWH). This study aims to investigate this association among WLWH and women at risk for HIV (WRH) in the United States. Methods and results: Data from 351 WLWH and 52 WRH participants from the Women's Interagency HIV Study having pocket depths and clinical periodontal attachment loss assessments in 2003–2004 were included. Multinomial logistic regression analyses in the full sample assessed the relationship between BMI (underweight/normal, overweight, or obese) and periodontitis by severity (mild, moderate, severe), adjusting for study sites, age, education, annual household income, smoking, alcohol consumption, and diabetes. Overall, 75.2% women (76.0% WLWH; 69.0% WRH) had periodontitis. Moreover, 75.0% obese and 75.3% overweight women were affected by periodontitis. In the full sample, adjusted odds ratio (aOR) of having mild, moderate, and severe periodontitis in obese women were: 1.14 (95% confidence interval [CI]: 0.51–2.52), 1.02 (95% CI: 0.46–2.29), and 0.24 (95% CI: 0.06–1.07), respectively, and in overweight women: 0.70 (95% CI: 0.31–1.58), 0.85 (95% CI: 0.38–1.90), and 0.31 (95% CI: 0.08–1.15), respectively. Conclusions: Even with high prevalence of periodontitis among women with or without HIV infection in this cohort, this study does not provide evidence of an association between BMI and periodontitis.
KW - BMI
KW - HIV
KW - obesity
KW - periodontal disease
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U2 - 10.1111/scd.12711
DO - 10.1111/scd.12711
M3 - Article
C2 - 35279851
AN - SCOPUS:85126095352
VL - 42
SP - 486
EP - 493
JO - Special Care in Dentistry
JF - Special Care in Dentistry
SN - 0275-1879
IS - 5
ER -