Assignment of human sprouty 4 gene to chromosome segment 5q32-33 and analysis of its pattern of expression

Hua Liu, Jin Zhong Chen, Shao Hua Gu, Jian Liang Dai, En Pang Zhao, Lu Huang, Wang Xiang Xu, Yi Xie, Yu Min Mao

Research output: Contribution to journalArticle

Abstract

The human sprouty 4 (SPYR4) gene was localized to chromosome band 5q32-33 by screening the Stanford radiation hybrid G3 panel using a SPRY4-specific primer pair for PCR. Northern blot analysis revealed two different mRNAs (5 kb and 2 kb) in liver, skeletal muscle, heart, lung, kidney, spleen, placenta and small intestine. Reverse transcriptase-PCR analysis showed that SPYR4 was expressed in all tested tissues to different levels.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalJournal of Genetics
Volume82
Issue number1-2
DOIs
StatePublished - Jan 1 2003

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Keywords

  • Expression pattern
  • Radioactive hybridization (RH)
  • SPRY4

ASJC Scopus subject areas

  • Genetics

Cite this

Liu, H., Chen, J. Z., Gu, S. H., Dai, J. L., Zhao, E. P., Huang, L., Xu, W. X., Xie, Y., & Mao, Y. M. (2003). Assignment of human sprouty 4 gene to chromosome segment 5q32-33 and analysis of its pattern of expression. Journal of Genetics, 82(1-2), 23-26. https://doi.org/10.1007/BF02715877