Arterial stenosis in migraine: Spasm or arteriopathy?

S. Solomon, Richard B. Lipton, P. Y. Harris

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Segmental arteral narrowing has rarely been angiographically demonstrated in patients with migraine. One new case is reported and 12 previous cases are reviewed. Though often referred to as vasospasm, arteriographic stenosis may result from edema of the vessel wall, arterial dissection, the effects of puerperium or arteritis. A biphasic course of spasm, similar to the pattern noted with subarachnoid hemorrhage, has been recorded in some migraineurs. The current neurogenic and biochemical concepts of ''spasm'' developed for subarachnoid hemorrhage are reviewed. Arterial narrowing may be important in several phenomena associated with migraine. It may account for migrainous cerebral infarction of hemorrhage. Vasoconstriction has also been invoked to explain the aura and other features of migraine. But the site of stenosis does not always correlate with the headache or focal neurologic features in location or timing. The angiographic changes are probably an epiphenomena rather than a primary mechanism of migraine. These changes may result from altered sympathetic neuronal activity; factors supporting that concept are reviewed.

Original languageEnglish (US)
Pages (from-to)52-61
Number of pages10
JournalHeadache
Volume30
Issue number2
StatePublished - 1990

Fingerprint

Spasm
Migraine Disorders
Pathologic Constriction
Subarachnoid Hemorrhage
Biochemical Phenomena
Arteritis
Cerebral Infarction
Cerebral Hemorrhage
Vasoconstriction
Postpartum Period
Nervous System
Headache
Dissection
Epilepsy
Edema

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Solomon, S., Lipton, R. B., & Harris, P. Y. (1990). Arterial stenosis in migraine: Spasm or arteriopathy? Headache, 30(2), 52-61.

Arterial stenosis in migraine : Spasm or arteriopathy? / Solomon, S.; Lipton, Richard B.; Harris, P. Y.

In: Headache, Vol. 30, No. 2, 1990, p. 52-61.

Research output: Contribution to journalArticle

Solomon, S, Lipton, RB & Harris, PY 1990, 'Arterial stenosis in migraine: Spasm or arteriopathy?', Headache, vol. 30, no. 2, pp. 52-61.
Solomon, S. ; Lipton, Richard B. ; Harris, P. Y. / Arterial stenosis in migraine : Spasm or arteriopathy?. In: Headache. 1990 ; Vol. 30, No. 2. pp. 52-61.
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