Are seizures really a problem after the use of antifibrinolytics?

Dmitry Rozin, Madelyn Kahana

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Antifibrinolytic therapy is important in hemostatic control during modern paediatric cardiac and non-cardiac surgery. There continues to be controversy regarding the available agents, e(epsilon)-aminocaproic acid and TXA, to utilize; whether there is a clearly superior choice. This discussion highlights the pharmacology differences between e(epsilon)-aminocaproic acid and TXA and reviews the data comparing the two drugs in paediatric cardiac surgical patients.

Original languageEnglish (US)
Title of host publicationYou're Wrong, I'm Right
Subtitle of host publicationDueling Authors Reexamine Classic Teachings in Anesthesia
PublisherSpringer International Publishing
Pages85-86
Number of pages2
ISBN (Electronic)9783319431697
ISBN (Print)9783319431673
DOIs
StatePublished - Jan 1 2016

Keywords

  • ?(epsilon)-aminocaproic acid
  • Antifibrinolytics
  • Neonatal anesthesia
  • Pediatric anesthesia
  • Pediatric cardiac anesthesia
  • Seizures
  • Tranexamic acid (TXA)

ASJC Scopus subject areas

  • General Medicine

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