Aquaporins in female specific cancers

Prameswari Kasa; Batoul Farran; Ganji Lakshmi Vara Prasad; Ganji Purnachandra Nagaraju

doi:10.1016/j.gene.2019.03.032

Aquaporins in female specific cancers

Prameswari Kasa, Batoul Farran, Ganji Lakshmi Vara Prasad, Ganji Purnachandra Nagaraju

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Aquaporins (AQPs) are hydrophobic integral trans-membrane channel proteins implicated in cellular proliferation and water transport in various cancers. They compose a family of 13 different isoforms (25–34 kDa) in mammals that have been identified to date. These AQPs exhibit a unique pattern of tissue expression. Though they can be found in most tissues, they are mostly active in endothelial and epithelial tissues. In this review, the AQPs associated with female-specific cancers are comprehensively explored and their significant features are analysed. Recent findings revealing their role in female-specific carcinogenesis, especially cervical, ovarian, uterine/endometrial, and breast, will be also discussed.

Original language	English (US)
Pages (from-to)	60-64
Number of pages	5
Journal	Gene
Volume	700
DOIs	https://doi.org/10.1016/j.gene.2019.03.032
State	Published - Jun 5 2019
Externally published	Yes

Keywords

Aquaporins
Breast cancer
Cervical cancer
Endometrial cancer
Ovarian cancer

ASJC Scopus subject areas

Genetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.gene.2019.03.032

Cite this

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title = "Aquaporins in female specific cancers",

abstract = "Aquaporins (AQPs) are hydrophobic integral trans-membrane channel proteins implicated in cellular proliferation and water transport in various cancers. They compose a family of 13 different isoforms (25–34 kDa) in mammals that have been identified to date. These AQPs exhibit a unique pattern of tissue expression. Though they can be found in most tissues, they are mostly active in endothelial and epithelial tissues. In this review, the AQPs associated with female-specific cancers are comprehensively explored and their significant features are analysed. Recent findings revealing their role in female-specific carcinogenesis, especially cervical, ovarian, uterine/endometrial, and breast, will be also discussed.",

keywords = "Aquaporins, Breast cancer, Cervical cancer, Endometrial cancer, Ovarian cancer",

author = "Prameswari Kasa and Batoul Farran and Prasad, {Ganji Lakshmi Vara} and Nagaraju, {Ganji Purnachandra}",

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year = "2019",

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doi = "10.1016/j.gene.2019.03.032",

language = "English (US)",

volume = "700",

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journal = "Gene",

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T1 - Aquaporins in female specific cancers

AU - Kasa, Prameswari

AU - Farran, Batoul

AU - Prasad, Ganji Lakshmi Vara

AU - Nagaraju, Ganji Purnachandra

PY - 2019/6/5

Y1 - 2019/6/5

N2 - Aquaporins (AQPs) are hydrophobic integral trans-membrane channel proteins implicated in cellular proliferation and water transport in various cancers. They compose a family of 13 different isoforms (25–34 kDa) in mammals that have been identified to date. These AQPs exhibit a unique pattern of tissue expression. Though they can be found in most tissues, they are mostly active in endothelial and epithelial tissues. In this review, the AQPs associated with female-specific cancers are comprehensively explored and their significant features are analysed. Recent findings revealing their role in female-specific carcinogenesis, especially cervical, ovarian, uterine/endometrial, and breast, will be also discussed.

AB - Aquaporins (AQPs) are hydrophobic integral trans-membrane channel proteins implicated in cellular proliferation and water transport in various cancers. They compose a family of 13 different isoforms (25–34 kDa) in mammals that have been identified to date. These AQPs exhibit a unique pattern of tissue expression. Though they can be found in most tissues, they are mostly active in endothelial and epithelial tissues. In this review, the AQPs associated with female-specific cancers are comprehensively explored and their significant features are analysed. Recent findings revealing their role in female-specific carcinogenesis, especially cervical, ovarian, uterine/endometrial, and breast, will be also discussed.

KW - Aquaporins

KW - Breast cancer

KW - Cervical cancer

KW - Endometrial cancer

KW - Ovarian cancer

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DO - 10.1016/j.gene.2019.03.032

M3 - Review article

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AN - SCOPUS:85063114917

SN - 0378-1119

VL - 700

SP - 60

EP - 64

JO - Gene

JF - Gene

ER -

Aquaporins in female specific cancers

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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