Applying recovery biomarkers to calibrate self-report measures of sodium and potassium in the Hispanic Community Health Study/Study of Latinos

Y. Mossavar-Rahmani, D. Sotres-Alvarez, W. W. Wong, C. M. Loria, M. D. Gellman, L. Van Horn, M. H. Alderman, J. M. Beasley, C. M. Lora, A. M. Siega-Riz, R. C. Kaplan, P. A. Shaw

Research output: Contribution to journalArticle

5 Scopus citations


Measurement error in assessment of sodium and potassium intake obscures associations with health outcomes. The level of this error in a diverse US Hispanic/Latino population is unknown. We investigated the measurement error in self-reported dietary intake of sodium and potassium and examined differences by background (Central American, Cuban, Dominican, Mexican, Puerto Rican and South American). In 2010-2012, we studied 447 participants aged 18-74 years from four communities (Miami, Bronx, Chicago and San Diego), obtaining objective 24-h urinary sodium and potassium excretion measures. Self-report was captured from two interviewer-administered 24-h dietary recalls. Twenty percent of the sample repeated the study. We examined bias in self-reported sodium and potassium from diet and the association of mismeasurement with participant characteristics. Linear regression relating self-report with objective measures was used to develop calibration equations. Self-report underestimated sodium intake by 19.8% and 20.8% and potassium intake by 1.3% and 4.6% in men and women, respectively. Sodium intake underestimation varied by Hispanic/Latino background (P<0.05) and was associated with higher body mass index (BMI). Potassium intake underestimation was associated with higher BMI, lower restaurant score (indicating lower consumption of foods prepared away from home and/or eaten outside the home) and supplement use. The R 2 was 19.7% and 25.0% for the sodium and potassium calibration models, respectively, increasing to 59.5 and 61.7% after adjusting for within-person variability in each biomarker. These calibration equations, corrected for subject-specific reporting error, have the potential to reduce bias in diet-disease associations within this largest cohort of Hispanics in the United States.

Original languageEnglish (US)
Pages (from-to)462-473
Number of pages12
JournalJournal of human hypertension
Issue number7
StatePublished - Jul 1 2017


ASJC Scopus subject areas

  • Internal Medicine

Cite this

Mossavar-Rahmani, Y., Sotres-Alvarez, D., Wong, W. W., Loria, C. M., Gellman, M. D., Van Horn, L., Alderman, M. H., Beasley, J. M., Lora, C. M., Siega-Riz, A. M., Kaplan, R. C., & Shaw, P. A. (2017). Applying recovery biomarkers to calibrate self-report measures of sodium and potassium in the Hispanic Community Health Study/Study of Latinos. Journal of human hypertension, 31(7), 462-473.