Apical ballooning syndrome associated with isolated severe hyponatremia: Case report and suggested pathophysiology

Ofer Sagiv, Sasa Vukelic, Steve Czak, Frank Messineo, Neil L. Coplan

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

An 82-year-old woman who presented to her primary care physician for preoperative evaluation was incidentally found to have severe hyponatremia (sodium = 118 mmol/L). The patient was then admitted for workup and treatment of hyponatremia. On day 2 of the admission, the patient was found to have new T-wave inversions on a telemetry monitor. Further workup, including an electrocardiogram, cardiac markers, echocardiogram, and a cardiac catheterization were consistent with the diagnosis of apical ballooning syndrome (ABS). Mechanisms of how severe hyponatremia may lead to ABS are discussed as well as a possible approach to the management of severe hyponatremia in postmenopausal women.

Original languageEnglish (US)
Pages (from-to)e198-e202
JournalReviews in Cardiovascular Medicine
Volume13
Issue number4
DOIs
StatePublished - 2012
Externally publishedYes

Keywords

  • Apical ballooning syndrome
  • Broken heart syndrome
  • Hyponatremia
  • Mechanism
  • Takotsubo cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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