Antiplatelet Agents and Arterial Thrombosis

Research output: Contribution to journalReview article

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Abstract

There is an increase in arterial thrombotic events in the elderly. Elderly patients are more likely to have associated diseases, such as diabetes, hypertension and hypercholesterolemia, and when age is confounded by these other predisposing factors, the risk of an arterial ischemic event increases disproportionately. Antithrombotic therapy for geriatric patients is underused, even when one adjusts for potential drug contraindications. This article focuses on the action of the currently available antiplatelet agents-aspirin, clopidogrel, and glycoprotein IIb/IIIa (GPIIb/IIIa) receptor antagonists, and assesses their effects in different disease states, with special attention to data that examine the geriatric population.

Original languageEnglish (US)
Pages (from-to)189-201
Number of pages13
JournalCardiology clinics
Volume26
Issue number2
DOIs
Publication statusPublished - May 1 2008

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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