Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: Años 2006, 2007 y 2008

Translated title of the contribution: Antimicrobial resistance of Gram negative bacilli isolated from terciary-care hospitals in Colombia

David Felipe Briceño, Adriana Correa, Carlos Valencia, Julián Andrés Torres, Robinson Pacheco, María Camila Montealegre, Diego Ospina, María Virginia Villegas

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Introduction: Antimicrobial resistance has been identified as one of the major public health problems worldwide. To facilitate its control, bacterial resistance levels must be monitored permanently by effective surveillance systems. Objective: To describe the antimicrobial resistance patterns of Gram negative bacilli in Colombian hospitals over a 3-year period. Materials and methods: This descriptive study used the bacterial susceptibility profiles provided by 14 tertiary-care hospitals belonging to the Colombian Nosocomial Resistance Study Group. The hospitals were located in 7 major cities in Colombia, and provided records over the period January 2006 to December 2008. Using WHONET 5.4, the antimicrobial resistance patterns were described for the Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenters (Pseudomonas aeruginosa and Acinetobacter baumannii). Comparisons were made in the bacterial responses to selected antibiotics in samples from general wards and from adult intensive care units. Results: The antimicrobial resistance frequencies of several Enterobacteriaceae species showed a decreasing trend. In contrast, P. aeruginosa was demonstrated to be a multidrug-resistance organism with increasing resistance frequencies. Conclusions: These data emphasize the importance of surveillance programs in detecting presence of multidrug-resistant organisms. This information will aid the implementation of protocols aimed to strengthen the infection control strategies and antibiotic stewardship in each hospital.

Translated title of the contributionAntimicrobial resistance of Gram negative bacilli isolated from terciary-care hospitals in Colombia
Original languageSpanish
Pages (from-to)371-381
Number of pages11
JournalBiomedica
Volume30
Issue number3
DOIs
StatePublished - 2010

Keywords

  • Bacterial
  • Colombia
  • Drug resistance
  • Epidemiologic surveillance
  • Gram-negative bacteria

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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