Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: Años 2006, 2007 y 2008

Translated title of the contribution: Antimicrobial resistance of Gram negative bacilli isolated from terciary-care hospitals in Colombia

David Felipe Briceño, Adriana Correa, Carlos Valencia, Julian A. Torres Isasiga, Robinson Pacheco, María Camila Montealegre, Diego Ospina, María Virginia Villegas

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Introduction: Antimicrobial resistance has been identified as one of the major public health problems worldwide. To facilitate its control, bacterial resistance levels must be monitored permanently by effective surveillance systems. Objective: To describe the antimicrobial resistance patterns of Gram negative bacilli in Colombian hospitals over a 3-year period. Materials and methods: This descriptive study used the bacterial susceptibility profiles provided by 14 tertiary-care hospitals belonging to the Colombian Nosocomial Resistance Study Group. The hospitals were located in 7 major cities in Colombia, and provided records over the period January 2006 to December 2008. Using WHONET 5.4, the antimicrobial resistance patterns were described for the Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenters (Pseudomonas aeruginosa and Acinetobacter baumannii). Comparisons were made in the bacterial responses to selected antibiotics in samples from general wards and from adult intensive care units. Results: The antimicrobial resistance frequencies of several Enterobacteriaceae species showed a decreasing trend. In contrast, P. aeruginosa was demonstrated to be a multidrug-resistance organism with increasing resistance frequencies. Conclusions: These data emphasize the importance of surveillance programs in detecting presence of multidrug-resistant organisms. This information will aid the implementation of protocols aimed to strengthen the infection control strategies and antibiotic stewardship in each hospital.

Original languageSpanish
Pages (from-to)371-381
Number of pages11
JournalBiomedica
Volume30
Issue number3
StatePublished - Jul 1 2010
Externally publishedYes

Fingerprint

Colombia
Bacilli
Bacillus
Enterobacteriaceae
Pseudomonas aeruginosa
Anti-Bacterial Agents
Enterobacter cloacae
Acinetobacter baumannii
Intensive care units
Patients' Rooms
Klebsiella pneumoniae
Multiple Drug Resistance
Public health
Tertiary Healthcare
Infection Control
Medical problems
Tertiary Care Centers
Escherichia coli
Intensive Care Units
Public Health

Keywords

  • Bacterial
  • Colombia
  • Drug resistance
  • Epidemiologic surveillance
  • Gram-negative bacteria

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Briceño, D. F., Correa, A., Valencia, C., Torres Isasiga, J. A., Pacheco, R., Montealegre, M. C., ... Villegas, M. V. (2010). Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: Años 2006, 2007 y 2008. Biomedica, 30(3), 371-381.

Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia : Años 2006, 2007 y 2008. / Briceño, David Felipe; Correa, Adriana; Valencia, Carlos; Torres Isasiga, Julian A.; Pacheco, Robinson; Montealegre, María Camila; Ospina, Diego; Villegas, María Virginia.

In: Biomedica, Vol. 30, No. 3, 01.07.2010, p. 371-381.

Research output: Contribution to journalArticle

Briceño, DF, Correa, A, Valencia, C, Torres Isasiga, JA, Pacheco, R, Montealegre, MC, Ospina, D & Villegas, MV 2010, 'Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: Años 2006, 2007 y 2008', Biomedica, vol. 30, no. 3, pp. 371-381.
Briceño, David Felipe ; Correa, Adriana ; Valencia, Carlos ; Torres Isasiga, Julian A. ; Pacheco, Robinson ; Montealegre, María Camila ; Ospina, Diego ; Villegas, María Virginia. / Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia : Años 2006, 2007 y 2008. In: Biomedica. 2010 ; Vol. 30, No. 3. pp. 371-381.
@article{0e17b0a70a2c4da8a4f418eb8ea9cd51,
title = "Actualizaci{\'o}n de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: A{\~n}os 2006, 2007 y 2008",
abstract = "Introduction: Antimicrobial resistance has been identified as one of the major public health problems worldwide. To facilitate its control, bacterial resistance levels must be monitored permanently by effective surveillance systems. Objective: To describe the antimicrobial resistance patterns of Gram negative bacilli in Colombian hospitals over a 3-year period. Materials and methods: This descriptive study used the bacterial susceptibility profiles provided by 14 tertiary-care hospitals belonging to the Colombian Nosocomial Resistance Study Group. The hospitals were located in 7 major cities in Colombia, and provided records over the period January 2006 to December 2008. Using WHONET 5.4, the antimicrobial resistance patterns were described for the Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenters (Pseudomonas aeruginosa and Acinetobacter baumannii). Comparisons were made in the bacterial responses to selected antibiotics in samples from general wards and from adult intensive care units. Results: The antimicrobial resistance frequencies of several Enterobacteriaceae species showed a decreasing trend. In contrast, P. aeruginosa was demonstrated to be a multidrug-resistance organism with increasing resistance frequencies. Conclusions: These data emphasize the importance of surveillance programs in detecting presence of multidrug-resistant organisms. This information will aid the implementation of protocols aimed to strengthen the infection control strategies and antibiotic stewardship in each hospital.",
keywords = "Bacterial, Colombia, Drug resistance, Epidemiologic surveillance, Gram-negative bacteria",
author = "Brice{\~n}o, {David Felipe} and Adriana Correa and Carlos Valencia and {Torres Isasiga}, {Julian A.} and Robinson Pacheco and Montealegre, {Mar{\'i}a Camila} and Diego Ospina and Villegas, {Mar{\'i}a Virginia}",
year = "2010",
month = "7",
day = "1",
language = "Spanish",
volume = "30",
pages = "371--381",
journal = "Biomedica",
issn = "0120-4157",
publisher = "Instituto Nacional de Salud",
number = "3",

}

TY - JOUR

T1 - Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia

T2 - Años 2006, 2007 y 2008

AU - Briceño, David Felipe

AU - Correa, Adriana

AU - Valencia, Carlos

AU - Torres Isasiga, Julian A.

AU - Pacheco, Robinson

AU - Montealegre, María Camila

AU - Ospina, Diego

AU - Villegas, María Virginia

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Introduction: Antimicrobial resistance has been identified as one of the major public health problems worldwide. To facilitate its control, bacterial resistance levels must be monitored permanently by effective surveillance systems. Objective: To describe the antimicrobial resistance patterns of Gram negative bacilli in Colombian hospitals over a 3-year period. Materials and methods: This descriptive study used the bacterial susceptibility profiles provided by 14 tertiary-care hospitals belonging to the Colombian Nosocomial Resistance Study Group. The hospitals were located in 7 major cities in Colombia, and provided records over the period January 2006 to December 2008. Using WHONET 5.4, the antimicrobial resistance patterns were described for the Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenters (Pseudomonas aeruginosa and Acinetobacter baumannii). Comparisons were made in the bacterial responses to selected antibiotics in samples from general wards and from adult intensive care units. Results: The antimicrobial resistance frequencies of several Enterobacteriaceae species showed a decreasing trend. In contrast, P. aeruginosa was demonstrated to be a multidrug-resistance organism with increasing resistance frequencies. Conclusions: These data emphasize the importance of surveillance programs in detecting presence of multidrug-resistant organisms. This information will aid the implementation of protocols aimed to strengthen the infection control strategies and antibiotic stewardship in each hospital.

AB - Introduction: Antimicrobial resistance has been identified as one of the major public health problems worldwide. To facilitate its control, bacterial resistance levels must be monitored permanently by effective surveillance systems. Objective: To describe the antimicrobial resistance patterns of Gram negative bacilli in Colombian hospitals over a 3-year period. Materials and methods: This descriptive study used the bacterial susceptibility profiles provided by 14 tertiary-care hospitals belonging to the Colombian Nosocomial Resistance Study Group. The hospitals were located in 7 major cities in Colombia, and provided records over the period January 2006 to December 2008. Using WHONET 5.4, the antimicrobial resistance patterns were described for the Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenters (Pseudomonas aeruginosa and Acinetobacter baumannii). Comparisons were made in the bacterial responses to selected antibiotics in samples from general wards and from adult intensive care units. Results: The antimicrobial resistance frequencies of several Enterobacteriaceae species showed a decreasing trend. In contrast, P. aeruginosa was demonstrated to be a multidrug-resistance organism with increasing resistance frequencies. Conclusions: These data emphasize the importance of surveillance programs in detecting presence of multidrug-resistant organisms. This information will aid the implementation of protocols aimed to strengthen the infection control strategies and antibiotic stewardship in each hospital.

KW - Bacterial

KW - Colombia

KW - Drug resistance

KW - Epidemiologic surveillance

KW - Gram-negative bacteria

UR - http://www.scopus.com/inward/record.url?scp=78650061835&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650061835&partnerID=8YFLogxK

M3 - Article

C2 - 21713339

AN - SCOPUS:78650061835

VL - 30

SP - 371

EP - 381

JO - Biomedica

JF - Biomedica

SN - 0120-4157

IS - 3

ER -