Antimicrobial agents, drug adverse reactions and interactions, and cancer

Ximena Millan, Victoria Muggia, Belinda Ostrowsky

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The intent of this chapter is to review the types of adverse drug reactions and interactions associated with antimicrobial agents, specifically in the setting of patients with malignancies. The initial sections will discuss categorizing and describing the mechanisms of adverse reactions and interactions. The later sections include a detailed discussion about adverse reactions and drug interactions associated with commonly used antibacterial, antiviral, and antifungal agents in this subpopulation. Where relevant, the clinical use and indication for the drugs will be reviewed. The antibacterial section will specifically address the emergence of antimicrobial resistance and drugs of last resort (newer agents, such as linezolid and daptomycin and novel uses of older previously retired agents, such as polymyxin B). The antifungal section will address the ramification of pharmacokinetic interactions and the need to measure drug levels. The chapter is not meant to be exhaustive and as such will not extensively address all antimicrobials or all interactions for each of these agents.

Original languageEnglish (US)
Pages (from-to)413-462
Number of pages50
JournalCancer Treatment and Research
Volume161
DOIs
StatePublished - 2014

Fingerprint

Linezolid
Anti-Infective Agents
Drug-Related Side Effects and Adverse Reactions
Drug Interactions
Daptomycin
Polymyxin B
Antifungal Agents
Microbial Drug Resistance
Pharmaceutical Preparations
Antiviral Agents
Neoplasms
Pharmacokinetics
Anti-Bacterial Agents

Keywords

  • Adverse reactions
  • Antimicrobials
  • Interactions

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Antimicrobial agents, drug adverse reactions and interactions, and cancer. / Millan, Ximena; Muggia, Victoria; Ostrowsky, Belinda.

In: Cancer Treatment and Research, Vol. 161, 2014, p. 413-462.

Research output: Contribution to journalArticle

Millan, Ximena ; Muggia, Victoria ; Ostrowsky, Belinda. / Antimicrobial agents, drug adverse reactions and interactions, and cancer. In: Cancer Treatment and Research. 2014 ; Vol. 161. pp. 413-462.
@article{4da5bd4ae4464b8b8e2eae38feb2b5a9,
title = "Antimicrobial agents, drug adverse reactions and interactions, and cancer",
abstract = "The intent of this chapter is to review the types of adverse drug reactions and interactions associated with antimicrobial agents, specifically in the setting of patients with malignancies. The initial sections will discuss categorizing and describing the mechanisms of adverse reactions and interactions. The later sections include a detailed discussion about adverse reactions and drug interactions associated with commonly used antibacterial, antiviral, and antifungal agents in this subpopulation. Where relevant, the clinical use and indication for the drugs will be reviewed. The antibacterial section will specifically address the emergence of antimicrobial resistance and drugs of last resort (newer agents, such as linezolid and daptomycin and novel uses of older previously retired agents, such as polymyxin B). The antifungal section will address the ramification of pharmacokinetic interactions and the need to measure drug levels. The chapter is not meant to be exhaustive and as such will not extensively address all antimicrobials or all interactions for each of these agents.",
keywords = "Adverse reactions, Antimicrobials, Interactions",
author = "Ximena Millan and Victoria Muggia and Belinda Ostrowsky",
year = "2014",
doi = "10.1007/978-3-319-04220-6_14",
language = "English (US)",
volume = "161",
pages = "413--462",
journal = "Cancer Treatment and Research",
issn = "0927-3042",
publisher = "Springer Netherlands",

}

TY - JOUR

T1 - Antimicrobial agents, drug adverse reactions and interactions, and cancer

AU - Millan, Ximena

AU - Muggia, Victoria

AU - Ostrowsky, Belinda

PY - 2014

Y1 - 2014

N2 - The intent of this chapter is to review the types of adverse drug reactions and interactions associated with antimicrobial agents, specifically in the setting of patients with malignancies. The initial sections will discuss categorizing and describing the mechanisms of adverse reactions and interactions. The later sections include a detailed discussion about adverse reactions and drug interactions associated with commonly used antibacterial, antiviral, and antifungal agents in this subpopulation. Where relevant, the clinical use and indication for the drugs will be reviewed. The antibacterial section will specifically address the emergence of antimicrobial resistance and drugs of last resort (newer agents, such as linezolid and daptomycin and novel uses of older previously retired agents, such as polymyxin B). The antifungal section will address the ramification of pharmacokinetic interactions and the need to measure drug levels. The chapter is not meant to be exhaustive and as such will not extensively address all antimicrobials or all interactions for each of these agents.

AB - The intent of this chapter is to review the types of adverse drug reactions and interactions associated with antimicrobial agents, specifically in the setting of patients with malignancies. The initial sections will discuss categorizing and describing the mechanisms of adverse reactions and interactions. The later sections include a detailed discussion about adverse reactions and drug interactions associated with commonly used antibacterial, antiviral, and antifungal agents in this subpopulation. Where relevant, the clinical use and indication for the drugs will be reviewed. The antibacterial section will specifically address the emergence of antimicrobial resistance and drugs of last resort (newer agents, such as linezolid and daptomycin and novel uses of older previously retired agents, such as polymyxin B). The antifungal section will address the ramification of pharmacokinetic interactions and the need to measure drug levels. The chapter is not meant to be exhaustive and as such will not extensively address all antimicrobials or all interactions for each of these agents.

KW - Adverse reactions

KW - Antimicrobials

KW - Interactions

UR - http://www.scopus.com/inward/record.url?scp=84902115682&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902115682&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-04220-6_14

DO - 10.1007/978-3-319-04220-6_14

M3 - Article

VL - 161

SP - 413

EP - 462

JO - Cancer Treatment and Research

JF - Cancer Treatment and Research

SN - 0927-3042

ER -