Antiangiogenic and antitumor activity of 6-(2-aminoethyl)amino-5- chlorouracil, a novel small-molecule inhibitor of thymidine phosphorylase, in combination with the vascular endothelial growth factor-trap

Medicine & Life Sciences

• 6-(2-aminoethyl)amino-5-chlorouracil 100%
• Thymidine Phosphorylase 58%
• Vascular Endothelial Growth Factor A 34%
• Neoplasms 12%
• Microvessels 8%
• Drug Delivery Systems 8%
• Heterografts 7%
• Vascular Endothelial Growth Factor Receptor 5%
• Angiogenesis Inducing Agents 4%
• Enzymes 4%
• Human Activities 4%
• Pancreatic Neoplasms 4%
• Non-Small Cell Lung Carcinoma 3%
• Oral Administration 3%
• Research Design 3%
• Growth 2%
• In Vitro Techniques 1%