Anthrax-associated shock

David L. Goldman, Arturo Casadevall

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Recent events have brought attention to the potential of Bacillus anthracis as an agent of bioterrorism. The shock like state of anthrax is invariably associated with high mortality, despite anti-microbial and supportive therapy. Multi-system dysfunction is typical, including: enhanced vascular permeability, hemorrhage and inflammation. Important questions concerning the pathophysiology of anthrax-associated shock remain unanswered, including the effects of B. anthracis infection on cardiac function. This review discusses the current state of knowledge regarding the pathophysiology of anthrax-associated shock.

Original languageEnglish (US)
Pages (from-to)4009-4014
Number of pages6
JournalFrontiers in Bioscience
Volume13
Issue number11
DOIs
StatePublished - 2008

Fingerprint

Biological Warfare Agents
Anthrax
Bacilli
Bacillus anthracis
Shock
Capillary Permeability
Hemorrhage
Inflammation
Mortality
Infection
Therapeutics

Keywords

  • Anthrax
  • Bacillus anthracis
  • Edema toxin
  • Lethal toxin
  • Review
  • Shock

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Anthrax-associated shock. / Goldman, David L.; Casadevall, Arturo.

In: Frontiers in Bioscience, Vol. 13, No. 11, 2008, p. 4009-4014.

Research output: Contribution to journalArticle

Goldman, DL & Casadevall, A 2008, 'Anthrax-associated shock', Frontiers in Bioscience, vol. 13, no. 11, pp. 4009-4014. https://doi.org/10.2741/2988
Goldman, David L. ; Casadevall, Arturo. / Anthrax-associated shock. In: Frontiers in Bioscience. 2008 ; Vol. 13, No. 11. pp. 4009-4014.
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