Anterior nasal resistance in obese children with obstructive sleep apnea syndrome

Sanghun Sin, David M. Wootton, Joseph M. McDonough, Kiran Nandalike, Raanan Arens

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives/Hypothesis To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome (OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI), and examine the association of gender and body mass index (BMI) with this measurement. Study Design Retrospective analysis. Methods Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in the supine position during tidal breathing. Thirty obese children with OSAS (aged 13.8 ± 2.6 years, BMI z score 2.6 ± 0.4) and 32 matched obese controls (aged 13.6 ± 2.3 years, BMI z score 2.4 ± 0.4), were studied. Unpaired t tests and Spearman correlation were performed. Results The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P = .012) and expiration (P = .003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r = 0.39, P = .04). The aNR did not correlate with BMI z score or with either gender. Conclusions We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspiration correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR may exist for obese children who exhibit OSAS.

Original languageEnglish (US)
Pages (from-to)2640-2644
Number of pages5
JournalLaryngoscope
Volume124
Issue number11
DOIs
StatePublished - Nov 1 2014

Fingerprint

Obstructive Sleep Apnea
Nose
Body Mass Index
Apnea
Rhinomanometry
Wakefulness
Supine Position
Sleep Apnea Syndromes
Respiration
Retrospective Studies

Keywords

  • Active anterior rhinomanometry
  • obesity
  • obstructive sleep apnea syndrome

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

Cite this

Anterior nasal resistance in obese children with obstructive sleep apnea syndrome. / Sin, Sanghun; Wootton, David M.; McDonough, Joseph M.; Nandalike, Kiran; Arens, Raanan.

In: Laryngoscope, Vol. 124, No. 11, 01.11.2014, p. 2640-2644.

Research output: Contribution to journalArticle

Sin, Sanghun ; Wootton, David M. ; McDonough, Joseph M. ; Nandalike, Kiran ; Arens, Raanan. / Anterior nasal resistance in obese children with obstructive sleep apnea syndrome. In: Laryngoscope. 2014 ; Vol. 124, No. 11. pp. 2640-2644.
@article{c6160acdd7084e28a43d084201ebb291,
title = "Anterior nasal resistance in obese children with obstructive sleep apnea syndrome",
abstract = "Objectives/Hypothesis To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome (OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI), and examine the association of gender and body mass index (BMI) with this measurement. Study Design Retrospective analysis. Methods Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in the supine position during tidal breathing. Thirty obese children with OSAS (aged 13.8 ± 2.6 years, BMI z score 2.6 ± 0.4) and 32 matched obese controls (aged 13.6 ± 2.3 years, BMI z score 2.4 ± 0.4), were studied. Unpaired t tests and Spearman correlation were performed. Results The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P = .012) and expiration (P = .003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r = 0.39, P = .04). The aNR did not correlate with BMI z score or with either gender. Conclusions We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspiration correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR may exist for obese children who exhibit OSAS.",
keywords = "Active anterior rhinomanometry, obesity, obstructive sleep apnea syndrome",
author = "Sanghun Sin and Wootton, {David M.} and McDonough, {Joseph M.} and Kiran Nandalike and Raanan Arens",
year = "2014",
month = "11",
day = "1",
doi = "10.1002/lary.24653",
language = "English (US)",
volume = "124",
pages = "2640--2644",
journal = "Laryngoscope",
issn = "0023-852X",
publisher = "John Wiley and Sons Inc.",
number = "11",

}

TY - JOUR

T1 - Anterior nasal resistance in obese children with obstructive sleep apnea syndrome

AU - Sin, Sanghun

AU - Wootton, David M.

AU - McDonough, Joseph M.

AU - Nandalike, Kiran

AU - Arens, Raanan

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Objectives/Hypothesis To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome (OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI), and examine the association of gender and body mass index (BMI) with this measurement. Study Design Retrospective analysis. Methods Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in the supine position during tidal breathing. Thirty obese children with OSAS (aged 13.8 ± 2.6 years, BMI z score 2.6 ± 0.4) and 32 matched obese controls (aged 13.6 ± 2.3 years, BMI z score 2.4 ± 0.4), were studied. Unpaired t tests and Spearman correlation were performed. Results The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P = .012) and expiration (P = .003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r = 0.39, P = .04). The aNR did not correlate with BMI z score or with either gender. Conclusions We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspiration correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR may exist for obese children who exhibit OSAS.

AB - Objectives/Hypothesis To evaluate nasal resistance in obese children with and without obstructive sleep apnea syndrome (OSAS), study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI), and examine the association of gender and body mass index (BMI) with this measurement. Study Design Retrospective analysis. Methods Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in the supine position during tidal breathing. Thirty obese children with OSAS (aged 13.8 ± 2.6 years, BMI z score 2.6 ± 0.4) and 32 matched obese controls (aged 13.6 ± 2.3 years, BMI z score 2.4 ± 0.4), were studied. Unpaired t tests and Spearman correlation were performed. Results The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (P = .012) and expiration (P = .003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r = 0.39, P = .04). The aNR did not correlate with BMI z score or with either gender. Conclusions We noted a higher aNR in obese children with OSAS as compared to obese controls, and the aNR on inspiration correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR may exist for obese children who exhibit OSAS.

KW - Active anterior rhinomanometry

KW - obesity

KW - obstructive sleep apnea syndrome

UR - http://www.scopus.com/inward/record.url?scp=84909995122&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84909995122&partnerID=8YFLogxK

U2 - 10.1002/lary.24653

DO - 10.1002/lary.24653

M3 - Article

VL - 124

SP - 2640

EP - 2644

JO - Laryngoscope

JF - Laryngoscope

SN - 0023-852X

IS - 11

ER -