Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

R. D. Jolly, K. E. Dittmer, B. R. Jones, A. J. Worth, K. G. Thompson, A. C. Johnstone, D. N. Palmer, N. S. Van de Water, K. M. Hemsley, D. J. Garrick, B. G. Winchester, S. U. Walkley

Research output: Contribution to journalReview articlepeer-review

Abstract

Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

Original languageEnglish (US)
Pages (from-to)255-266
Number of pages12
JournalNew Zealand Veterinary Journal
Volume69
Issue number5
DOIs
StatePublished - 2021

Keywords

  • animal model
  • animals
  • Genetic disorder
  • genetic screening
  • lysosomal storage disease

ASJC Scopus subject areas

  • veterinary(all)

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