An improved measurement of progesterone in saliva and clinical applications

K. M. Weidenheim, C. J. Anderson, D. S. Sgoutas, D. E. Mitchell

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Measurement of progesterone in saliva offers several advantages when compared to assays of serum progesterone, especially when ovarian activity is being assessed. Most published methods for the determination of progesterone in saliva are based on assays developed in research centers, which imploy 'in-house' reagents that are critically dependent on supplies of highly selected antisera. In this report, the adaptation of a readily available commercial progesterone 'kit', the Pantex Immunodirect Progesterone (125I) is described for the measurement of salivary progesterone. A single extraction step was added, however, to improve assay performance and to ensure that total salivary progesterone was measured.

Original languageEnglish (US)
Pages (from-to)245-254
Number of pages10
JournalAnnals of Clinical and Laboratory Science
Volume16
Issue number3
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

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