An immunoperoxidase study on herpes simplex virus encephalitis

Toshiro Kumanishi, Asao Hirano

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Using formalin-fixed, paraffin-embedded sections, indirect immunoperoxidase studies were performed on 3 autopsied and 1 biopsied cases of herpes simplex virus (HSV) encephalitis. Specific reaction was observed in all 4 cases. Distinct stain was observed both in neurons and in glial cells. Electron microscopic studies performed on the same material revealed HSV particles stained with electron-dense reaction products. The advantages and disadvantages of the use of formalin-fixed, paraffin embedded material in immunoperoxidase studies of viral disease are discussed.

Original languageEnglish (US)
Pages (from-to)790-795
Number of pages6
JournalJournal of Neuropathology and Experimental Neurology
Volume37
Issue number6
StatePublished - 1978

Fingerprint

Herpes Simplex Encephalitis
Simplexvirus
Paraffin
Formaldehyde
Electrons
Virus Diseases
Neuroglia
Virion
Coloring Agents
Neurons

ASJC Scopus subject areas

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Cellular and Molecular Neuroscience
  • Neurology
  • Neuroscience(all)

Cite this

An immunoperoxidase study on herpes simplex virus encephalitis. / Kumanishi, Toshiro; Hirano, Asao.

In: Journal of Neuropathology and Experimental Neurology, Vol. 37, No. 6, 1978, p. 790-795.

Research output: Contribution to journalArticle

Kumanishi, Toshiro ; Hirano, Asao. / An immunoperoxidase study on herpes simplex virus encephalitis. In: Journal of Neuropathology and Experimental Neurology. 1978 ; Vol. 37, No. 6. pp. 790-795.
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