An evolutionary framework for treating pediatric sarcomas

Damon R. Reed, Jonathan Metts, Mariyah Pressley, Brooke L. Fridley, Masanori Hayashi, Michael S. Isakoff, David M. Loeb, Rikesh Makanji, Ryan D. Roberts, Matteo Trucco, Lars M. Wagner, Mark G. Alexandrow, Robert A. Gatenby, Joel S. Brown

Research output: Contribution to journalComment/debate

Original languageEnglish (US)
Pages (from-to)2577-2587
Number of pages11
JournalCancer
Volume126
Issue number11
DOIs
StateAccepted/In press - Jan 1 2020

Keywords

  • Ewing sarcoma
  • adaptive therapy
  • clinical trial
  • evolution
  • extinction therapy
  • first strike
  • osteosarcoma
  • resistance
  • rhabdomyosarcoma
  • second strike

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Reed, D. R., Metts, J., Pressley, M., Fridley, B. L., Hayashi, M., Isakoff, M. S., Loeb, D. M., Makanji, R., Roberts, R. D., Trucco, M., Wagner, L. M., Alexandrow, M. G., Gatenby, R. A., & Brown, J. S. (Accepted/In press). An evolutionary framework for treating pediatric sarcomas. Cancer, 126(11), 2577-2587. https://doi.org/10.1002/cncr.32777