An additional dehydratase-like activity is required for Lankacidin antibiotic biosynthesis

Jeroen S. Dickschat, Olivia M. Vergnolle, Hui Hong, Stephen Garner, Susanna R. Bidgood, Hannah C. Dooley, Zixin Deng, Peter F. Leadlay, Yuhui Sun

Research output: Contribution to journalArticle

11 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)2408-2412
Number of pages5
JournalChemBioChem
Volume12
Issue number16
DOIs
StatePublished - Nov 4 2011
Externally publishedYes

Fingerprint

Molecular Sequence Data
Polyketide Synthases
Hydro-Lyases
Polyketides
Sequence Alignment
Biosynthesis
Macrolides
Streptomyces
Tertiary Protein Structure
Amino Acid Sequence
Anti-Bacterial Agents
Mutation

Keywords

  • Antibiotics
  • Biosynthesis
  • Dehydratase
  • Polyketides
  • Streptomyces

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Molecular Medicine
  • Molecular Biology
  • Medicine(all)

Cite this

Dickschat, J. S., Vergnolle, O. M., Hong, H., Garner, S., Bidgood, S. R., Dooley, H. C., ... Sun, Y. (2011). An additional dehydratase-like activity is required for Lankacidin antibiotic biosynthesis. ChemBioChem, 12(16), 2408-2412. https://doi.org/10.1002/cbic.201100474

An additional dehydratase-like activity is required for Lankacidin antibiotic biosynthesis. / Dickschat, Jeroen S.; Vergnolle, Olivia M.; Hong, Hui; Garner, Stephen; Bidgood, Susanna R.; Dooley, Hannah C.; Deng, Zixin; Leadlay, Peter F.; Sun, Yuhui.

In: ChemBioChem, Vol. 12, No. 16, 04.11.2011, p. 2408-2412.

Research output: Contribution to journalArticle

Dickschat, JS, Vergnolle, OM, Hong, H, Garner, S, Bidgood, SR, Dooley, HC, Deng, Z, Leadlay, PF & Sun, Y 2011, 'An additional dehydratase-like activity is required for Lankacidin antibiotic biosynthesis', ChemBioChem, vol. 12, no. 16, pp. 2408-2412. https://doi.org/10.1002/cbic.201100474
Dickschat, Jeroen S. ; Vergnolle, Olivia M. ; Hong, Hui ; Garner, Stephen ; Bidgood, Susanna R. ; Dooley, Hannah C. ; Deng, Zixin ; Leadlay, Peter F. ; Sun, Yuhui. / An additional dehydratase-like activity is required for Lankacidin antibiotic biosynthesis. In: ChemBioChem. 2011 ; Vol. 12, No. 16. pp. 2408-2412.
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