Alternatively spliced human genes by exon skipping - A database (ASHESdb)

Meena Kishore Sakharkar, Bagavathi S. Perumal, Yun Ping Lim, Lee Pern Chern, Yiting Yu, Pandjassarame Kangueane

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. Exon skipping is the most commonly known alternative splicing mechanism. A comprehensive database of alternative splicing by exon skipping is made available for the human genome data. 1,229 human genes are identified to exhibit alternative splicing by exon skipping.

Original languageEnglish (US)
Pages (from-to)221-225
Number of pages5
JournalIn Silico Biology
Volume5
Issue number3
StatePublished - Aug 24 2005

Keywords

  • Alternative splicing
  • Computational analysis
  • Database
  • Eukaryotic gene structure
  • Exon skipping
  • Full length cDNA sequences
  • Genome wide splicing
  • Multiple splice variants
  • Protein diversity
  • Protein isoforms
  • Skipping patterns
  • Tissue specificity

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Computational Mathematics
  • Computational Theory and Mathematics

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  • Cite this

    Sakharkar, M. K., Perumal, B. S., Lim, Y. P., Chern, L. P., Yu, Y., & Kangueane, P. (2005). Alternatively spliced human genes by exon skipping - A database (ASHESdb). In Silico Biology, 5(3), 221-225.