Alternatively spliced human genes by exon skipping - A database (ASHESdb)

Meena Kishore Sakharkar, Bagavathi S. Perumal, Yun Ping Lim, Lee Pern Chern, Yiting Yu, Pandjassarame Kangueane

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. Exon skipping is the most commonly known alternative splicing mechanism. A comprehensive database of alternative splicing by exon skipping is made available for the human genome data. 1,229 human genes are identified to exhibit alternative splicing by exon skipping.

Original languageEnglish (US)
Pages (from-to)221-225
Number of pages5
JournalIn Silico Biology
Volume5
Issue number3
StatePublished - 2005
Externally publishedYes

Fingerprint

Alternative Splicing
Recombinant DNA
Exons
Genes
Databases
Gene
Human Genome
Messenger RNA
Genome
Coding
Human

Keywords

  • Alternative splicing
  • Computational analysis
  • Database
  • Eukaryotic gene structure
  • Exon skipping
  • Full length cDNA sequences
  • Genome wide splicing
  • Multiple splice variants
  • Protein diversity
  • Protein isoforms
  • Skipping patterns
  • Tissue specificity

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Sakharkar, M. K., Perumal, B. S., Lim, Y. P., Chern, L. P., Yu, Y., & Kangueane, P. (2005). Alternatively spliced human genes by exon skipping - A database (ASHESdb). In Silico Biology, 5(3), 221-225.

Alternatively spliced human genes by exon skipping - A database (ASHESdb). / Sakharkar, Meena Kishore; Perumal, Bagavathi S.; Lim, Yun Ping; Chern, Lee Pern; Yu, Yiting; Kangueane, Pandjassarame.

In: In Silico Biology, Vol. 5, No. 3, 2005, p. 221-225.

Research output: Contribution to journalArticle

Sakharkar, MK, Perumal, BS, Lim, YP, Chern, LP, Yu, Y & Kangueane, P 2005, 'Alternatively spliced human genes by exon skipping - A database (ASHESdb)', In Silico Biology, vol. 5, no. 3, pp. 221-225.
Sakharkar MK, Perumal BS, Lim YP, Chern LP, Yu Y, Kangueane P. Alternatively spliced human genes by exon skipping - A database (ASHESdb). In Silico Biology. 2005;5(3):221-225.
Sakharkar, Meena Kishore ; Perumal, Bagavathi S. ; Lim, Yun Ping ; Chern, Lee Pern ; Yu, Yiting ; Kangueane, Pandjassarame. / Alternatively spliced human genes by exon skipping - A database (ASHESdb). In: In Silico Biology. 2005 ; Vol. 5, No. 3. pp. 221-225.
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