Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy

Toru Kawanami, Takeo Kato, Josephina F. Llena, Asao Hirano, Hideo Sasaki

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We examined the inferior olivary nucleus from four cases of olivary hypertrophy and six control cases immunohistochemically with an anti-synaptophysin (SYP) antibody. Our study revealed the altered SYP-immunoreactive pattern in the hypertrophied olives, consisting of an increased number of SYP-immunoreactive dots on neuronal cell bodies in spite of its decreased immunoreactivity in the neuropil. Because SYP is a marker protein for presynaptic vesicles, presynaptic terminals in the inferior olivary nucleus seem to change their distribution during the course of olivary hypertrophy.

Original languageEnglish (US)
Pages (from-to)178-180
Number of pages3
JournalNeuroscience Letters
Volume176
Issue number2
DOIs
StatePublished - Aug 1 1994

Fingerprint

Synaptophysin
Olivary Nucleus
Hypertrophy
Neuropil
Presynaptic Terminals
Olea
Anti-Idiotypic Antibodies
Proteins

Keywords

  • Immunohistochemistry
  • Inferior olivary nucleus
  • Olivary hypertrophy
  • Presynaptic terminal
  • Synapse
  • Synaptic reorganization
  • Synaptophysin

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Kawanami, T., Kato, T., Llena, J. F., Hirano, A., & Sasaki, H. (1994). Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy. Neuroscience Letters, 176(2), 178-180. https://doi.org/10.1016/0304-3940(94)90076-0

Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy. / Kawanami, Toru; Kato, Takeo; Llena, Josephina F.; Hirano, Asao; Sasaki, Hideo.

In: Neuroscience Letters, Vol. 176, No. 2, 01.08.1994, p. 178-180.

Research output: Contribution to journalArticle

Kawanami, T, Kato, T, Llena, JF, Hirano, A & Sasaki, H 1994, 'Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy', Neuroscience Letters, vol. 176, no. 2, pp. 178-180. https://doi.org/10.1016/0304-3940(94)90076-0
Kawanami, Toru ; Kato, Takeo ; Llena, Josephina F. ; Hirano, Asao ; Sasaki, Hideo. / Altered synaptophysin-immunoreactive pattern in human olivary hypertrophy. In: Neuroscience Letters. 1994 ; Vol. 176, No. 2. pp. 178-180.
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