Altered biodistribution of radiopharmaceuticals used in bone scintigraphy

Lionel S. Zuckier, Patrick Martineau

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Bone scintigraphy has remained a mainstay of clinical nuclear medicine for more than 4 decades. Extensive medical literature has developed surrounding the etiology and significance of alterations in distribution of bone radiopharmaceuticals. Altered biodistribution may be of a global nature, reflecting altered partition of radiopharmaceutical between bone and soft tissues, or more focal, reflecting regional abnormalities, including those related to bone or soft tissues. A third category of alterations in the distribution of bone radiopharmaceuticals is those due to errors and blunders, colloquially termed "artifactual" in the medical imaging literature. Being cognizant of these unexpected abnormalities, and understanding their etiology, will prepare the reader to more readily appreciate the significance of these findings when encountered in clinical practice.

Original languageEnglish (US)
Pages (from-to)81-96
Number of pages16
JournalSeminars in nuclear medicine
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Radiopharmaceuticals
Radionuclide Imaging
Bone and Bones
Clinical Medicine
Nuclear Medicine
Diagnostic Imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Altered biodistribution of radiopharmaceuticals used in bone scintigraphy. / Zuckier, Lionel S.; Martineau, Patrick.

In: Seminars in nuclear medicine, Vol. 45, No. 1, 01.01.2015, p. 81-96.

Research output: Contribution to journalArticle

@article{3413807e6e9e43449b40a68cec3f421d,
title = "Altered biodistribution of radiopharmaceuticals used in bone scintigraphy",
abstract = "Bone scintigraphy has remained a mainstay of clinical nuclear medicine for more than 4 decades. Extensive medical literature has developed surrounding the etiology and significance of alterations in distribution of bone radiopharmaceuticals. Altered biodistribution may be of a global nature, reflecting altered partition of radiopharmaceutical between bone and soft tissues, or more focal, reflecting regional abnormalities, including those related to bone or soft tissues. A third category of alterations in the distribution of bone radiopharmaceuticals is those due to errors and blunders, colloquially termed {"}artifactual{"} in the medical imaging literature. Being cognizant of these unexpected abnormalities, and understanding their etiology, will prepare the reader to more readily appreciate the significance of these findings when encountered in clinical practice.",
author = "Zuckier, {Lionel S.} and Patrick Martineau",
year = "2015",
month = "1",
day = "1",
doi = "10.1053/j.semnuclmed.2014.07.007",
language = "English (US)",
volume = "45",
pages = "81--96",
journal = "Seminars in Nuclear Medicine",
issn = "0001-2998",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Altered biodistribution of radiopharmaceuticals used in bone scintigraphy

AU - Zuckier, Lionel S.

AU - Martineau, Patrick

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Bone scintigraphy has remained a mainstay of clinical nuclear medicine for more than 4 decades. Extensive medical literature has developed surrounding the etiology and significance of alterations in distribution of bone radiopharmaceuticals. Altered biodistribution may be of a global nature, reflecting altered partition of radiopharmaceutical between bone and soft tissues, or more focal, reflecting regional abnormalities, including those related to bone or soft tissues. A third category of alterations in the distribution of bone radiopharmaceuticals is those due to errors and blunders, colloquially termed "artifactual" in the medical imaging literature. Being cognizant of these unexpected abnormalities, and understanding their etiology, will prepare the reader to more readily appreciate the significance of these findings when encountered in clinical practice.

AB - Bone scintigraphy has remained a mainstay of clinical nuclear medicine for more than 4 decades. Extensive medical literature has developed surrounding the etiology and significance of alterations in distribution of bone radiopharmaceuticals. Altered biodistribution may be of a global nature, reflecting altered partition of radiopharmaceutical between bone and soft tissues, or more focal, reflecting regional abnormalities, including those related to bone or soft tissues. A third category of alterations in the distribution of bone radiopharmaceuticals is those due to errors and blunders, colloquially termed "artifactual" in the medical imaging literature. Being cognizant of these unexpected abnormalities, and understanding their etiology, will prepare the reader to more readily appreciate the significance of these findings when encountered in clinical practice.

UR - http://www.scopus.com/inward/record.url?scp=84919458774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919458774&partnerID=8YFLogxK

U2 - 10.1053/j.semnuclmed.2014.07.007

DO - 10.1053/j.semnuclmed.2014.07.007

M3 - Article

C2 - 25475381

AN - SCOPUS:84919458774

VL - 45

SP - 81

EP - 96

JO - Seminars in Nuclear Medicine

JF - Seminars in Nuclear Medicine

SN - 0001-2998

IS - 1

ER -