Alteplase in the treatment of complicated parapneumonic effusion: a case report.

Naomi B. Bishop, Steven Pon, H. Michael Ushay, Bruce M. Greenwald

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21 Scopus citations

Abstract

The treatment of complex parapneumonic effusions in children remains controversial, with some advocating less invasive, strictly medical management and others supporting a more aggressive approach of thoracotomy with or without decortication. Recent advances, including video-assisted thoracoscopic surgery and intrapleural fibrinolytic therapy, offer new options for effective treatment. We report the first case of successful resolution of a complex parapneumonic effusion in a 16-month-old girl with the use of tissue plasminogen activator (alteplase), infused via a catheter in the pleural space.

Original languageEnglish (US)
Pages (from-to)E188-190
JournalPediatrics
Volume111
Issue number2
Publication statusPublished - Feb 2003
Externally publishedYes

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bishop, N. B., Pon, S., Ushay, H. M., & Greenwald, B. M. (2003). Alteplase in the treatment of complicated parapneumonic effusion: a case report. Pediatrics, 111(2), E188-190.