Alteplase in the treatment of complicated parapneumonic effusion: a case report.

Naomi B. Bishop, Steven Pon, Henry Michael Ushay, Bruce M. Greenwald

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The treatment of complex parapneumonic effusions in children remains controversial, with some advocating less invasive, strictly medical management and others supporting a more aggressive approach of thoracotomy with or without decortication. Recent advances, including video-assisted thoracoscopic surgery and intrapleural fibrinolytic therapy, offer new options for effective treatment. We report the first case of successful resolution of a complex parapneumonic effusion in a 16-month-old girl with the use of tissue plasminogen activator (alteplase), infused via a catheter in the pleural space.

Original languageEnglish (US)
JournalPediatrics
Volume111
Issue number2
StatePublished - Feb 2003
Externally publishedYes

Fingerprint

Tissue Plasminogen Activator
Video-Assisted Thoracic Surgery
Thrombolytic Therapy
Thoracotomy
Catheters
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Alteplase in the treatment of complicated parapneumonic effusion : a case report. / Bishop, Naomi B.; Pon, Steven; Ushay, Henry Michael; Greenwald, Bruce M.

In: Pediatrics, Vol. 111, No. 2, 02.2003.

Research output: Contribution to journalArticle

Bishop, Naomi B. ; Pon, Steven ; Ushay, Henry Michael ; Greenwald, Bruce M. / Alteplase in the treatment of complicated parapneumonic effusion : a case report. In: Pediatrics. 2003 ; Vol. 111, No. 2.
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