TY - JOUR
T1 - Allergic fungal sinusitis in the pediatric population
AU - Kupferberg, Stephen B.
AU - Bent, John P.
PY - 1996/12
Y1 - 1996/12
N2 - Objective: To determine the optimal treatment in pediatric patients with allergic fungal sinusitis (AFS). Design: A retrospective review of 10 patients diagnosed as having AFS. Setting: Academic tertiary medical center. Patients: Pediatric patients who fulfilled 5 criteria necessary for diagnosis of AFS: (1) type 1 hypersensitivity; (2) nasal polyposis; (3) characteristic computed tomographic scan; (4) histological evidence of eosinophilic mucus without evidence of fungal invasion into sinus tissue; and (5) a positive fungal stain or culture of sinus contents. Treatment: All patients were treated with functional endoscopic sinus surgery with removal of fungal debris. Adjuvant therapy included nasal irrigations, postoperative endoscopic cleanings, and systemic corticosteroids in 9 of 10 patients. Mean Outcome Measure: Clinical disease monitored endoscopically by means of an objective staging system. Results: Five patients were without disease (stage 0), 1 had allergic mucin and mucosal edema (stage 1), 1 had allergic mucin and polypoid edema (stage II), and 3 had polyps and/or fungal debris (stage III). Conclusions: The treatment and prognosis of pediatric AFS are similar to those of adult AFS. However, systemic corticosteroids should be weaned aggressively in children to minimize complications, particularly long-term growth retardation.
AB - Objective: To determine the optimal treatment in pediatric patients with allergic fungal sinusitis (AFS). Design: A retrospective review of 10 patients diagnosed as having AFS. Setting: Academic tertiary medical center. Patients: Pediatric patients who fulfilled 5 criteria necessary for diagnosis of AFS: (1) type 1 hypersensitivity; (2) nasal polyposis; (3) characteristic computed tomographic scan; (4) histological evidence of eosinophilic mucus without evidence of fungal invasion into sinus tissue; and (5) a positive fungal stain or culture of sinus contents. Treatment: All patients were treated with functional endoscopic sinus surgery with removal of fungal debris. Adjuvant therapy included nasal irrigations, postoperative endoscopic cleanings, and systemic corticosteroids in 9 of 10 patients. Mean Outcome Measure: Clinical disease monitored endoscopically by means of an objective staging system. Results: Five patients were without disease (stage 0), 1 had allergic mucin and mucosal edema (stage 1), 1 had allergic mucin and polypoid edema (stage II), and 3 had polyps and/or fungal debris (stage III). Conclusions: The treatment and prognosis of pediatric AFS are similar to those of adult AFS. However, systemic corticosteroids should be weaned aggressively in children to minimize complications, particularly long-term growth retardation.
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U2 - 10.1001/archotol.1996.01890240087019
DO - 10.1001/archotol.1996.01890240087019
M3 - Article
C2 - 8956755
AN - SCOPUS:0029906202
SN - 0886-4470
VL - 122
SP - 1381
EP - 1384
JO - Archives of Otolaryngology - Head and Neck Surgery
JF - Archives of Otolaryngology - Head and Neck Surgery
IS - 12
ER -