Allergic contact dermatitis elicitation thresholds of potent allergens in humans

E. Jerschow, J. J. Hostýnek, H. I. Maibach

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Literature scoured for human allergenicity to individual chemicals yields a limited number of potent sensitizers, which can be classified in four categories: metals, botanicals, biocides and miscellany. Potency is defined as strong for substances eliciting eczematous reactions to patch concentrations of 500 ppm (parts per million) or less in sensitized individuals. Most data encountered stem from studies conducted on dermatology patients tested routinely for hypersensitivity; only few data have been generated by systematic serial dilution testing.

Original languageEnglish (US)
Pages (from-to)1095-1108
Number of pages14
JournalFood and Chemical Toxicology
Volume39
Issue number11
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Keywords

  • Allergic contact dermatitis
  • Biocides
  • Elicitation
  • Human
  • Metals
  • Patch test
  • Threshold concentration

ASJC Scopus subject areas

  • Food Science
  • Toxicology

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