Allergic contact dermatitis elicitation thresholds of potent allergens in humans

E. Jerschow; J. J. Hostýnek; H. I. Maibach

doi:10.1016/S0278-6915(01)00059-X

Allergic contact dermatitis elicitation thresholds of potent allergens in humans

E. Jerschow, J. J. Hostýnek, H. I. Maibach

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Literature scoured for human allergenicity to individual chemicals yields a limited number of potent sensitizers, which can be classified in four categories: metals, botanicals, biocides and miscellany. Potency is defined as strong for substances eliciting eczematous reactions to patch concentrations of 500 ppm (parts per million) or less in sensitized individuals. Most data encountered stem from studies conducted on dermatology patients tested routinely for hypersensitivity; only few data have been generated by systematic serial dilution testing.

Original language	English (US)
Pages (from-to)	1095-1108
Number of pages	14
Journal	Food and Chemical Toxicology
Volume	39
Issue number	11
DOIs	https://doi.org/10.1016/S0278-6915(01)00059-X
State	Published - 2001
Externally published	Yes

Keywords

Allergic contact dermatitis
Biocides
Elicitation
Human
Metals
Patch test
Threshold concentration

ASJC Scopus subject areas

Food Science
Toxicology

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10.1016/S0278-6915(01)00059-X

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title = "Allergic contact dermatitis elicitation thresholds of potent allergens in humans",

abstract = "Literature scoured for human allergenicity to individual chemicals yields a limited number of potent sensitizers, which can be classified in four categories: metals, botanicals, biocides and miscellany. Potency is defined as strong for substances eliciting eczematous reactions to patch concentrations of 500 ppm (parts per million) or less in sensitized individuals. Most data encountered stem from studies conducted on dermatology patients tested routinely for hypersensitivity; only few data have been generated by systematic serial dilution testing.",

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AU - Maibach, H. I.

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AB - Literature scoured for human allergenicity to individual chemicals yields a limited number of potent sensitizers, which can be classified in four categories: metals, botanicals, biocides and miscellany. Potency is defined as strong for substances eliciting eczematous reactions to patch concentrations of 500 ppm (parts per million) or less in sensitized individuals. Most data encountered stem from studies conducted on dermatology patients tested routinely for hypersensitivity; only few data have been generated by systematic serial dilution testing.

KW - Allergic contact dermatitis

KW - Biocides

KW - Elicitation

KW - Human

KW - Metals

KW - Patch test

KW - Threshold concentration

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ER -

Allergic contact dermatitis elicitation thresholds of potent allergens in humans

Abstract

Keywords

ASJC Scopus subject areas

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