Alcohol and risk of breast cancer in mexican women

Jeannette M. Beasley, Gloria D. Coronado, Jennifer Livaudais, Angélica Angeles-Llerenas, Carolina Ortega-Olvera, Isabelle Romieu, Eduardo Lazcano-Ponce, Gabriela Torres-Mejía

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Background Little is known about the relationship between alcohol intake and breast cancer risk among Mexican women. This association may be modified by folate and Vitamin B12. Methods A population-based case-control study conducted in Mexico recruited 1,000 incident breast cancer cases aged 35-69 and 1,074 controls matched on age, region, and health care system. In-person interviews were conducted to assess breast cancer risk factors and recent diet using a food frequency questionnaire. Conditional logistic regression models estimated adjusted odds ratios and 95% confidence intervals. Results Over one-half (57%) of cases and less than onehalf of controls (45%) reported any lifetime alcohol consumption. Compared with never drinkers, women reporting ever drinking (Adjusted OR = 1.25, 95% CI = 0.99-1.58) had a greater odds of breast cancer. There was evidence for interaction in the association between ever consuming any alcohol and breast cancer by folate (p for interaction = 0.04) suggesting women with lower folate intake had a higher odds of breast cancer (Adjusted OR = 1.99, 95% CI = 1.26-3.16) compared to women with higher folate intake (OR = 1.12, 95% CI = 0.69-1.83). Conclusions Our findings support evidence that any alcohol intake increases risk of breast cancer. Insufficient intake of folate may further elevate risk for developing breast cancer among women who consume alcohol.

Original languageEnglish (US)
Pages (from-to)863-870
Number of pages8
JournalCancer Causes and Control
Volume21
Issue number6
DOIs
StatePublished - Jun 2010
Externally publishedYes

Fingerprint

Alcohols
Breast Neoplasms
Folic Acid
Logistic Models
Vitamin B 12
Mexico
Alcohol Drinking
Drinking
Case-Control Studies
Odds Ratio
Confidence Intervals
Interviews
Diet
Delivery of Health Care
Food
Population

Keywords

  • Alcohol consumption
  • Breast cancer
  • Folate and vitamin B12
  • Hispanic
  • Mexican women

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Beasley, J. M., Coronado, G. D., Livaudais, J., Angeles-Llerenas, A., Ortega-Olvera, C., Romieu, I., ... Torres-Mejía, G. (2010). Alcohol and risk of breast cancer in mexican women. Cancer Causes and Control, 21(6), 863-870. https://doi.org/10.1007/s10552-010-9513-x

Alcohol and risk of breast cancer in mexican women. / Beasley, Jeannette M.; Coronado, Gloria D.; Livaudais, Jennifer; Angeles-Llerenas, Angélica; Ortega-Olvera, Carolina; Romieu, Isabelle; Lazcano-Ponce, Eduardo; Torres-Mejía, Gabriela.

In: Cancer Causes and Control, Vol. 21, No. 6, 06.2010, p. 863-870.

Research output: Contribution to journalArticle

Beasley, JM, Coronado, GD, Livaudais, J, Angeles-Llerenas, A, Ortega-Olvera, C, Romieu, I, Lazcano-Ponce, E & Torres-Mejía, G 2010, 'Alcohol and risk of breast cancer in mexican women', Cancer Causes and Control, vol. 21, no. 6, pp. 863-870. https://doi.org/10.1007/s10552-010-9513-x
Beasley JM, Coronado GD, Livaudais J, Angeles-Llerenas A, Ortega-Olvera C, Romieu I et al. Alcohol and risk of breast cancer in mexican women. Cancer Causes and Control. 2010 Jun;21(6):863-870. https://doi.org/10.1007/s10552-010-9513-x
Beasley, Jeannette M. ; Coronado, Gloria D. ; Livaudais, Jennifer ; Angeles-Llerenas, Angélica ; Ortega-Olvera, Carolina ; Romieu, Isabelle ; Lazcano-Ponce, Eduardo ; Torres-Mejía, Gabriela. / Alcohol and risk of breast cancer in mexican women. In: Cancer Causes and Control. 2010 ; Vol. 21, No. 6. pp. 863-870.
@article{ca775cc987fb4bb2b72022e4f5f21140,
title = "Alcohol and risk of breast cancer in mexican women",
abstract = "Background Little is known about the relationship between alcohol intake and breast cancer risk among Mexican women. This association may be modified by folate and Vitamin B12. Methods A population-based case-control study conducted in Mexico recruited 1,000 incident breast cancer cases aged 35-69 and 1,074 controls matched on age, region, and health care system. In-person interviews were conducted to assess breast cancer risk factors and recent diet using a food frequency questionnaire. Conditional logistic regression models estimated adjusted odds ratios and 95{\%} confidence intervals. Results Over one-half (57{\%}) of cases and less than onehalf of controls (45{\%}) reported any lifetime alcohol consumption. Compared with never drinkers, women reporting ever drinking (Adjusted OR = 1.25, 95{\%} CI = 0.99-1.58) had a greater odds of breast cancer. There was evidence for interaction in the association between ever consuming any alcohol and breast cancer by folate (p for interaction = 0.04) suggesting women with lower folate intake had a higher odds of breast cancer (Adjusted OR = 1.99, 95{\%} CI = 1.26-3.16) compared to women with higher folate intake (OR = 1.12, 95{\%} CI = 0.69-1.83). Conclusions Our findings support evidence that any alcohol intake increases risk of breast cancer. Insufficient intake of folate may further elevate risk for developing breast cancer among women who consume alcohol.",
keywords = "Alcohol consumption, Breast cancer, Folate and vitamin B12, Hispanic, Mexican women",
author = "Beasley, {Jeannette M.} and Coronado, {Gloria D.} and Jennifer Livaudais and Ang{\'e}lica Angeles-Llerenas and Carolina Ortega-Olvera and Isabelle Romieu and Eduardo Lazcano-Ponce and Gabriela Torres-Mej{\'i}a",
year = "2010",
month = "6",
doi = "10.1007/s10552-010-9513-x",
language = "English (US)",
volume = "21",
pages = "863--870",
journal = "Cancer Causes and Control",
issn = "0957-5243",
publisher = "Springer Netherlands",
number = "6",

}

TY - JOUR

T1 - Alcohol and risk of breast cancer in mexican women

AU - Beasley, Jeannette M.

AU - Coronado, Gloria D.

AU - Livaudais, Jennifer

AU - Angeles-Llerenas, Angélica

AU - Ortega-Olvera, Carolina

AU - Romieu, Isabelle

AU - Lazcano-Ponce, Eduardo

AU - Torres-Mejía, Gabriela

PY - 2010/6

Y1 - 2010/6

N2 - Background Little is known about the relationship between alcohol intake and breast cancer risk among Mexican women. This association may be modified by folate and Vitamin B12. Methods A population-based case-control study conducted in Mexico recruited 1,000 incident breast cancer cases aged 35-69 and 1,074 controls matched on age, region, and health care system. In-person interviews were conducted to assess breast cancer risk factors and recent diet using a food frequency questionnaire. Conditional logistic regression models estimated adjusted odds ratios and 95% confidence intervals. Results Over one-half (57%) of cases and less than onehalf of controls (45%) reported any lifetime alcohol consumption. Compared with never drinkers, women reporting ever drinking (Adjusted OR = 1.25, 95% CI = 0.99-1.58) had a greater odds of breast cancer. There was evidence for interaction in the association between ever consuming any alcohol and breast cancer by folate (p for interaction = 0.04) suggesting women with lower folate intake had a higher odds of breast cancer (Adjusted OR = 1.99, 95% CI = 1.26-3.16) compared to women with higher folate intake (OR = 1.12, 95% CI = 0.69-1.83). Conclusions Our findings support evidence that any alcohol intake increases risk of breast cancer. Insufficient intake of folate may further elevate risk for developing breast cancer among women who consume alcohol.

AB - Background Little is known about the relationship between alcohol intake and breast cancer risk among Mexican women. This association may be modified by folate and Vitamin B12. Methods A population-based case-control study conducted in Mexico recruited 1,000 incident breast cancer cases aged 35-69 and 1,074 controls matched on age, region, and health care system. In-person interviews were conducted to assess breast cancer risk factors and recent diet using a food frequency questionnaire. Conditional logistic regression models estimated adjusted odds ratios and 95% confidence intervals. Results Over one-half (57%) of cases and less than onehalf of controls (45%) reported any lifetime alcohol consumption. Compared with never drinkers, women reporting ever drinking (Adjusted OR = 1.25, 95% CI = 0.99-1.58) had a greater odds of breast cancer. There was evidence for interaction in the association between ever consuming any alcohol and breast cancer by folate (p for interaction = 0.04) suggesting women with lower folate intake had a higher odds of breast cancer (Adjusted OR = 1.99, 95% CI = 1.26-3.16) compared to women with higher folate intake (OR = 1.12, 95% CI = 0.69-1.83). Conclusions Our findings support evidence that any alcohol intake increases risk of breast cancer. Insufficient intake of folate may further elevate risk for developing breast cancer among women who consume alcohol.

KW - Alcohol consumption

KW - Breast cancer

KW - Folate and vitamin B12

KW - Hispanic

KW - Mexican women

UR - http://www.scopus.com/inward/record.url?scp=77955631524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955631524&partnerID=8YFLogxK

U2 - 10.1007/s10552-010-9513-x

DO - 10.1007/s10552-010-9513-x

M3 - Article

C2 - 20155314

AN - SCOPUS:77955631524

VL - 21

SP - 863

EP - 870

JO - Cancer Causes and Control

JF - Cancer Causes and Control

SN - 0957-5243

IS - 6

ER -