Aging: One thing leads to another

Marion Schmidt, Brian K. Kennedy

Research output: Contribution to journalShort survey

6 Scopus citations

Abstract

Mitochondria deteriorate during the aging process, but the underlying mechanisms for the decline of this critical organelle are unknown. A new study indicates that in yeast an age-dependent reduction in vacuolar acidification leads to mitochondrial dysfunction through a surprising mechanism: loss of vacuolar neutral amino acid transport.

Original languageEnglish (US)
Pages (from-to)R1048-R1051
JournalCurrent Biology
Volume22
Issue number24
DOIs
StatePublished - Dec 18 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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    Schmidt, M., & Kennedy, B. K. (2012). Aging: One thing leads to another. Current Biology, 22(24), R1048-R1051. https://doi.org/10.1016/j.cub.2012.11.016