Affinity measured by microcluster

David R. Fooksman, Michael L. Dustin

Research output: Contribution to journalComment/debate

1 Scopus citations

Abstract

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Original languageEnglish (US)
Pages (from-to)907-909
Number of pages3
JournalJournal of Experimental Medicine
Volume207
Issue number5
DOIs
StatePublished - May 10 2010
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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