Adverse childhood experiences and lifetime adverse maternal outcomes (gestational diabetes and hypertensive disorders of pregnancy) in the Hispanic Community Health Study/Study of Latinos

Kaitlyn K. Stanhope, Alison L. Cammack, Krista M. Perreira, Lindsay Fernández-Rhodes, Christina Cordero, Linda C. Gallo, Carmen R. Isasi, Sheila F. Castañeda, Martha L. Daviglus, Michelle A. Kominiarek, Shakira S. Suglia

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Childhood adversity is associated with increased risk of adult disease, including type II diabetes and hypertension. However, little is known about potential associations between childhood adversity and adverse pregnancy outcomes. The goal of this study was to examine the relationship between adverse childhood experiences (ACEs) and ever experiencing gestational diabetes mellitus (GDM) or a hypertensive disorder of pregnancy (HDP) in a cohort of Hispanic or Latina women. Methods: We analyzed data from 2319 women from the Hispanic Community Health Study/Study of Latinos who had ever given birth to a liveborn infant. We fit separate logistic regression models accounting for sample weights to examine the association between ACEs and risk of GDM and HDP adjusting for Hispanic/Latino background, age at immigration to the United States, and education. Results: Women who reported four or more ACEs did not show increased odds of GDM or HDP compared with those who reported three or fewer (GDM adjusted odds ratio: 0.8 [0.5, 1.3]; HDP adjusted OR: 1.0 [0.7, 1.5]). Conclusions: Unlike previous research with majority non-Hispanic White cohorts, there was no association between ACEs and GDM or HDP. Future research should explore if this relationship varies by race/ethnicity in multiethnic cohorts.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalAnnals of Epidemiology
Volume50
DOIs
StatePublished - Oct 2020

Keywords

  • Childhood adversity
  • Gestational diabetes
  • Hypertensive disorders of pregnancy

ASJC Scopus subject areas

  • Epidemiology

Fingerprint

Dive into the research topics of 'Adverse childhood experiences and lifetime adverse maternal outcomes (gestational diabetes and hypertensive disorders of pregnancy) in the Hispanic Community Health Study/Study of Latinos'. Together they form a unique fingerprint.

Cite this