Advances of stem cell based-therapeutic approaches for tendon repair

Lidi Liu, Jennifer Hindieh, Daniel J. Leong, Hui (Herb) Sun

Research output: Contribution to journalReview article

9 Scopus citations

Abstract

Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalJournal of Orthopaedic Translation
Volume9
DOIs
StatePublished - Apr 1 2017

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Keywords

  • stem cells
  • tendinopathy
  • tendon repair

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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