Advances of stem cell based-therapeutic approaches for tendon repair

Lidi Liu, Jennifer Hindieh, Daniel J. Leong, Hui (Herb) Sun

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalJournal of Orthopaedic Translation
Volume9
DOIs
StatePublished - Apr 1 2017

Fingerprint

Tendons
Stem Cells
Cell- and Tissue-Based Therapy
Tendon Injuries
Rupture
Therapeutics
Direction compound

Keywords

  • stem cells
  • tendinopathy
  • tendon repair

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Advances of stem cell based-therapeutic approaches for tendon repair. / Liu, Lidi; Hindieh, Jennifer; Leong, Daniel J.; Sun, Hui (Herb).

In: Journal of Orthopaedic Translation, Vol. 9, 01.04.2017, p. 69-75.

Research output: Contribution to journalReview article

Liu, Lidi ; Hindieh, Jennifer ; Leong, Daniel J. ; Sun, Hui (Herb). / Advances of stem cell based-therapeutic approaches for tendon repair. In: Journal of Orthopaedic Translation. 2017 ; Vol. 9. pp. 69-75.
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