Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation

Howard Doyle, Ignazio R. Marino, Adelaida Miro, Victor Scott, Maureen Martin, John Fung, David Kramer, Thomas E. Starzl

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The adult respiratory distress syndrome (ARDS) com­plicating liver failure carries a 100% mortality. Two cases of ARDS that resolved following liver transplantation have been reported, one associated with acute allograft rejection, and the second due to sepsis. There is, however, a great reluctance to transplant these very-high-risk patients. We report the first series of patients with ARDS secondary to liver failure who successfully underwent OLTX. No patient had sepsis or pneumonia. Posttransplant mechanical ventilation was required for a median of 14 days (range 6-37 days). All patients in this series are alive and well, with a follow-up of 6-15 months. This demonstrates that ARDS associated with liver failure, an otherwise uniformly lethal complica­tion, can respond dramatically to OLTX.

Original languageEnglish (US)
Pages (from-to)292-296
Number of pages5
JournalTransplantation
Volume55
Issue number2
StatePublished - 1993
Externally publishedYes

Fingerprint

Adult Respiratory Distress Syndrome
Liver Transplantation
Liver Failure
Liver
Sepsis
Artificial Respiration
Allografts
Pneumonia
Transplants
Mortality

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Doyle, H., Marino, I. R., Miro, A., Scott, V., Martin, M., Fung, J., ... Starzl, T. E. (1993). Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation. Transplantation, 55(2), 292-296.

Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation. / Doyle, Howard; Marino, Ignazio R.; Miro, Adelaida; Scott, Victor; Martin, Maureen; Fung, John; Kramer, David; Starzl, Thomas E.

In: Transplantation, Vol. 55, No. 2, 1993, p. 292-296.

Research output: Contribution to journalArticle

Doyle, H, Marino, IR, Miro, A, Scott, V, Martin, M, Fung, J, Kramer, D & Starzl, TE 1993, 'Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation', Transplantation, vol. 55, no. 2, pp. 292-296.
Doyle, Howard ; Marino, Ignazio R. ; Miro, Adelaida ; Scott, Victor ; Martin, Maureen ; Fung, John ; Kramer, David ; Starzl, Thomas E. / Adult respiratory distress syndrome secondary to end-stage liver disease—successful outcome following liver transplantation. In: Transplantation. 1993 ; Vol. 55, No. 2. pp. 292-296.
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