Adrenergic signaling in heart failure and cardiovascular aging

Gaetano Santulli, Guido Iaccarino

Research output: Contribution to journalReview article

49 Scopus citations

Abstract

Both cardiovascular disease and aging are associated with changes in the sympathetic nervous system. Indeed, mounting evidence indicates that adrenergic receptors are functionally involved in numerous processes underlying both aging and cardiovascular disorders, in particular heart failure. This article will review the pathophysiological role of the sympathetic nervous system in heart failure and cardiovascular aging.

Original languageEnglish (US)
Pages (from-to)65-72
Number of pages8
JournalMaturitas
Volume93
DOIs
StatePublished - Nov 1 2016

Keywords

  • Aging
  • Beta adrenergic receptors
  • Cardiovascular system
  • G protein-coupled receptor kinases
  • Heart failure
  • Multimorbidity
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Obstetrics and Gynecology

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