Adrenergic Receptors

M. Ciccarelli; D. Sorriento; E. Coscioni; G. Iaccarino; G. Santulli

doi:10.1016/B978-0-12-803111-7.00011-7

Adrenergic Receptors

M. Ciccarelli, D. Sorriento, E. Coscioni, G. Iaccarino, G. Santulli

Research output: Chapter in Book/Report/Conference proceeding › Chapter

31 Scopus citations

Abstract

This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including hypertension, heart failure, and metabolism. The chapter is concluded by an updated overview on the pharmacological options available in the clinical scenario to obtain a proper blockade of adrenergic receptors.

Original language	English (US)
Title of host publication	Endocrinology of the Heart in Health and Disease
Subtitle of host publication	Integrated, Cellular, and Molecular Endocrinology of the Heart
Publisher	Elsevier Inc.
Pages	285-315
Number of pages	31
ISBN (Electronic)	9780128031124
ISBN (Print)	9780128031117
DOIs	https://doi.org/10.1016/B978-0-12-803111-7.00011-7
State	Published - 2017
Externally published	Yes

Keywords

Adrenergic receptors
Alpha blockers
Beta blockers
Cardiomyocytes
Endothelium
GRKs
Heart failure
Hypertension
Metabolism
Mitochondria
Nitroxidative stress
ROS
Sympathetic nervous system

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-803111-7.00011-7

Cite this

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title = "Adrenergic Receptors",

abstract = "This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including hypertension, heart failure, and metabolism. The chapter is concluded by an updated overview on the pharmacological options available in the clinical scenario to obtain a proper blockade of adrenergic receptors.",

keywords = "Adrenergic receptors, Alpha blockers, Beta blockers, Cardiomyocytes, Endothelium, GRKs, Heart failure, Hypertension, Metabolism, Mitochondria, Nitroxidative stress, ROS, Sympathetic nervous system",

author = "M. Ciccarelli and D. Sorriento and E. Coscioni and G. Iaccarino and G. Santulli",

year = "2017",

doi = "10.1016/B978-0-12-803111-7.00011-7",

language = "English (US)",

isbn = "9780128031117",

pages = "285--315",

booktitle = "Endocrinology of the Heart in Health and Disease",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Adrenergic Receptors

AU - Ciccarelli, M.

AU - Sorriento, D.

AU - Coscioni, E.

AU - Iaccarino, G.

AU - Santulli, G.

PY - 2017

Y1 - 2017

N2 - This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including hypertension, heart failure, and metabolism. The chapter is concluded by an updated overview on the pharmacological options available in the clinical scenario to obtain a proper blockade of adrenergic receptors.

AB - This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including hypertension, heart failure, and metabolism. The chapter is concluded by an updated overview on the pharmacological options available in the clinical scenario to obtain a proper blockade of adrenergic receptors.

KW - Adrenergic receptors

KW - Alpha blockers

KW - Beta blockers

KW - Cardiomyocytes

KW - Endothelium

KW - GRKs

KW - Heart failure

KW - Hypertension

KW - Metabolism

KW - Mitochondria

KW - Nitroxidative stress

KW - ROS

KW - Sympathetic nervous system

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UR - http://www.scopus.com/inward/citedby.url?scp=85021921782&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-803111-7.00011-7

DO - 10.1016/B978-0-12-803111-7.00011-7

M3 - Chapter

AN - SCOPUS:85021921782

SN - 9780128031117

SP - 285

EP - 315

BT - Endocrinology of the Heart in Health and Disease

PB - Elsevier Inc.

ER -

Adrenergic Receptors

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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