Adrenal chromaffin granules and secretory granules from thyroid parafollicular cells have several common antigens

Rosa Weiler, Shulamit Cidon, Michael D. Gershon, Hadassah Tamir, Ruth Hogue-Angeletti, Hans Winkler

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The presence of various antigens in two types of isolated endocrine vesicles (chromaffin granules and secretory vesicles of thyroid parafollicular cells) was investigated by immunoblotting. The twotypes of vesicles have three common secretory proteins: chromogranin A, chromogranin B and secretogranin II. Furthermore, six common membrane antigens were found: cytochrome b-561, carboxypeptidase H, glycoprotein II, glycoprotein III, synaptin/synaptophysin and SV 2. These results demonstrate that vesicles obtained from neural crest-derived endocrine cells not only share several common secretory peptides and proteins, but also have common properties as far as their membrane antigens are concerned.

Original languageEnglish (US)
Pages (from-to)457-459
Number of pages3
JournalFEBS Letters
Volume257
Issue number2
DOIs
StatePublished - Nov 6 1989

Fingerprint

Chromaffin Granules
Secretory Vesicles
Thyroid Gland
Antigens
Glycoproteins
Secretogranin II
Carboxypeptidase H
Chromogranin B
Membranes
Chromogranin A
Synaptophysin
Endocrine Cells
Neural Crest
Immunoblotting
Proteins
Cells
Peptides

Keywords

  • Chromaffin granule
  • Chromogranin A
  • Chromogranin B
  • Cytochrome b-561
  • Parafollicular cell thyroid
  • Synaptin
  • Synaptophysin

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Weiler, R., Cidon, S., Gershon, M. D., Tamir, H., Hogue-Angeletti, R., & Winkler, H. (1989). Adrenal chromaffin granules and secretory granules from thyroid parafollicular cells have several common antigens. FEBS Letters, 257(2), 457-459. https://doi.org/10.1016/0014-5793(89)81595-9

Adrenal chromaffin granules and secretory granules from thyroid parafollicular cells have several common antigens. / Weiler, Rosa; Cidon, Shulamit; Gershon, Michael D.; Tamir, Hadassah; Hogue-Angeletti, Ruth; Winkler, Hans.

In: FEBS Letters, Vol. 257, No. 2, 06.11.1989, p. 457-459.

Research output: Contribution to journalArticle

Weiler, R, Cidon, S, Gershon, MD, Tamir, H, Hogue-Angeletti, R & Winkler, H 1989, 'Adrenal chromaffin granules and secretory granules from thyroid parafollicular cells have several common antigens', FEBS Letters, vol. 257, no. 2, pp. 457-459. https://doi.org/10.1016/0014-5793(89)81595-9
Weiler, Rosa ; Cidon, Shulamit ; Gershon, Michael D. ; Tamir, Hadassah ; Hogue-Angeletti, Ruth ; Winkler, Hans. / Adrenal chromaffin granules and secretory granules from thyroid parafollicular cells have several common antigens. In: FEBS Letters. 1989 ; Vol. 257, No. 2. pp. 457-459.
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