Adamantinoma-like Ewing Sarcoma of the thyroid gland: Cytomorphologic, phenotypic and molecular features

Ijeuru Chikeka, Simon Sung, Patricia Tiscornia-Wasserman, Adela Cimic

Research output: Contribution to journalArticlepeer-review

Abstract

Adamantinoma-like Ewing Sarcoma (ALES) is a rare subtype of Ewing sarcoma family of tumors (EFTs) which are defined by their EWSR1 gene rearrangements. We present a case of a 15-year old female with a swelling in her anterior neck of 4 months duration which had recently begun to rapidly grow in size. Fine needle aspiration showed a small blue round cell tumor with immunoreactivity for cytokeratin, CD99 and FLI1. Material for molecular testing was available on the resection specimen. Demonstration of t(11;22) (EWS-FLI1) was helpful in establishing the diagnosis.

Original languageEnglish (US)
Pages (from-to)1107-1110
Number of pages4
JournalDiagnostic Cytopathology
Volume48
Issue number11
DOIs
StatePublished - Nov 1 2020

Keywords

  • adamantinoma-like Ewing sarcoma
  • cytology
  • thyroid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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