Be My Guest: Two acyclic cucurbit[n]uril-type receptors that carry SO 3--groups bind tightly to several commonly used neuromuscular blocking agents, such as rocuronium, in aqueous solution as revealed by direct and competitive UV/Vis binding assays. One of these containers functions as a potent reversal agent for rocuronium-induced neuromuscular block in rats.
- host-guest systems
- medicinal chemistry
- molecular recognition
- neuromuscular blocking agents
ASJC Scopus subject areas