Acute stent recoil and optimal balloon inflation strategy: An experimental study using real-time optical coherence tomography

Hideki Kitahara, Katsuhisa Waseda, Ryotaro Yamada, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Kozo Okada, Teruyoshi Kume, Kaori Nakagawa, Tomohiko Teramoto, Fumiaki Ikeno, Paul G. Yock, Peter J. Fitzgerald, Yasuhiro Honda

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Aims: Our aim was to evaluate stent expansion and acute recoil at deployment and post-dilatation, and the impact of post-dilatation strategies on final stent dimensions. Methods and results: Optical coherence tomography (OCT) was performed on eight bare metal platforms of drug-eluting stents (3.0 mm diameter, n=6 for each) during and after balloon inflation in a silicone mock vessel. After nominal-pressure deployment, a single long (30 sec) vs. multiple short (10 sec x3) post-dilatations were performed using a non-compliant balloon (3.25 mm, 20 atm). Stent areas during deployment with original delivery systems were smaller in stainless steel stents than in cobalt-chromium and platinum-chromium stents (p<0.001), whereas subsequent acute recoil was comparable among the three materials. At post-dilatation, acute recoil was greater in cobalt-chromium and platinum-chromium stents than in stainless steel stents (p<0.001), resulting in smaller final stent areas in cobalt-chromium and platinum-chromium stents than in stainless steel stents (p<0.001). In comparison between conventional and latest-generation cobalt-chromium stents, stent areas were not significantly different after both deployment and post-dilatation. With multiple short post-dilatations, acute recoil was significantly improved from first to third short inflation (p<0.001), achieving larger final area than a single long inflation, despite stent materials/designs (p<0.001). Conclusions: Real-time OCT revealed significant acute recoil in all stent types. Both stent materials/designs and post-dilatation strategies showed a significant impact on final stent expansion.

Original languageEnglish (US)
Pages (from-to)e190-e198
JournalEuroIntervention
Volume12
Issue number2
DOIs
StatePublished - Jun 2016
Externally publishedYes

Keywords

  • Experimental
  • Optical coherence tomography
  • Stent designs

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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