Adult dog kidneys were transplanted to neonatal puppies with survival of the recipients and function of the transplant. The acute changes in cardiac output, blood volume, central venous, and systemic arterial pressures were neither significant nor consistent. The large tissue volume of the transplant appeared to have no serious adverse effect on the puppy's cardiovascular system. These experiments support the feasibility of transplanting adult kidneys to neonates with inadequate renal function.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health