@article{1c80a11033054c27b2ee201183abc6dd,
title = "Activity-dependent plasticity of electrical synapses: Increasing evidence for its presence and functional roles in the mammalian brain",
abstract = "Gap junctions mediate electrical synaptic transmission between neurons. While the actions of neurotransmitter modulators on the conductance of gap junctions have been extensively documented, increasing evidence indicates they can also be influenced by the ongoing activity of neural networks, in most cases via local interactions with nearby glutamatergic synapses. We review here early evidence for the existence of activity-dependent regulatory mechanisms as well recent examples reported in mammalian brain. The ubiquitous distribution of both neuronal connexins and the molecules involved suggest this phenomenon is widespread and represents a property of electrical transmission in general.",
author = "Haas, {Julie S.} and Greenwald, {Corey M.} and Pereda, {Alberto E.}",
note = "Funding Information: Publication charges for this work was partly funded by the Brain & Behavior Research Foundation and by the Whitehall Foundation to JSH, and partly funded by NS0552827 to AEP. This article has been published as part of BMC Cell Biology Volume 17 Supplement 1, 2016: Proceedings of the International Gap Junction Conference 2015. The full contents of the supplement are available online at http://bmccellbiol.biomedcentral.com/articles/supplements/volume-17-supplement-1. Funding Information: JSH was supported in part as the Haddie Investigator, with a 2014 NARSAD Young Investigator Grant from the Brain & Behavior Research Foundation, and by the Whitehall Foundation. AEP was supported by National Institutes of Health grants DC03186, DC011099, NS055726, NS085772 and NS0552827. Publisher Copyright: {\textcopyright} 2016 Haas et al.",
year = "2016",
month = may,
day = "24",
doi = "10.1186/s12860-016-0090-z",
language = "English (US)",
volume = "17",
journal = "BMC Cell Biology",
issn = "1471-2121",
publisher = "BioMed Central",
number = "1",
}