Activation of MAPK and FoxO by Manganese (Mn) in rat neonatal primary astrocyte cultures

Agriculture & Biology

• astrocytes 100%
• manganese 77%
• neonates 69%
• phosphorylation 26%
• mitogen-activated protein kinase 24%
• neurotoxicity 18%
• oxidative stress 17%
• insulin 13%
• stress response 12%
• manganese chloride 11%
• peroxisome proliferator-activated receptor gamma 10%
• Parkinson disease 10%
• manganese dioxide 10%
• environmental exposure 9%
• neurodegenerative diseases 9%
• redox potential 8%
• information processing 8%
• carboxylic acids 7%
• glutathione peroxidase 7%
• cultured cells 7%
• cytosol 6%
• biomarkers 6%
• cysteine 6%
• reactive oxygen species 6%
• superoxide dismutase 5%
• transcription factors 5%
• pretreatment 5%
• brain 5%
• toxicity 5%
• dosage 3%
• proteins 2%
• cells 2%

Medicine & Life Sciences

• Manganese 98%
• Astrocytes 75%
• Phosphorylation 20%
• Oxidative Stress 16%
• 2-oxothiazolidine-4-carboxylic acid 13%
• Winged-Helix Transcription Factors 12%
• glutathione peroxidase GPX1 11%
• manganese chloride 11%
• superoxide dismutase 2 10%
• Insulin 10%
• Forkhead Transcription Factors 9%
• SB 203580 9%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 8%
• PPAR gamma 8%
• Environmental Exposure 8%
• Neuroprotection 7%
• p38 Mitogen-Activated Protein Kinases 7%
• Electronic Data Processing 7%
• Cytosol 7%
• Oxidation-Reduction 7%
• Cysteine 7%
• Superoxide Dismutase 6%
• Neurodegenerative Diseases 6%
• Cultured Cells 6%
• Parkinson Disease 6%
• Reactive Oxygen Species 6%
• Poisons 5%
• Biomarkers 4%
• Brain 3%
• Proteins 2%

Chemical Compounds

• Oxidative Stress 35%
• Neurotoxicity 29%
• Superoxide 11%
• Redox Potential 11%
• Reactive Oxygen Metabolite 11%
• Biological Marker 10%
• Glutathione 10%
• Peroxidase 10%
• Cysteine 10%
• Toxic 8%
• Protein 4%
• Acid 4%