Activation of a voltage-insensitive conductance by inward calcium current

W. Clusin, D. C. Spray, M. V.L. Bennett

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


ELECTRICAL excitability is more complex in cell bodies than in axons. In various nerve cells there is a voltage-sensitive permeability to calcium as well as to sodium and potassium. Furthermore, increased calcium in the cytoplasm of nerve cell bodies increases their potassium permeability. In voltage-clamped Helix neurones, Meech and Standen1,2 reported that a substantial fraction of the potassium conductance activated during a depolarisation depends on an inward calcium current.

Original languageEnglish (US)
Pages (from-to)425-427
Number of pages3
Issue number5516
StatePublished - 1975
Externally publishedYes

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